Micelles structure development as a strategy to improve smart cancer therapy

NAN Hanafy, M El-Kemary, S Leporatti - Cancers, 2018 - mdpi.com
Micelles as colloidal suspension have attracted considerable attention due to their potential
use for both cancer diagnosis and therapy. These structures have proven their ability to …

[HTML][HTML] Computational and experimental approaches for investigating nanoparticle-based drug delivery systems

M Ramezanpour, SSW Leung… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Most therapeutic agents suffer from poor solubility, rapid clearance from the blood stream, a
lack of targeting, and often poor translocation ability across cell membranes. Drug/gene …

Dynamical and phase behavior of a phospholipid membrane altered by an antimicrobial peptide at low concentration

VK Sharma, E Mamontov, M Tyagi, S Qian… - The journal of …, 2016 - ACS Publications
The mechanism of action of antimicrobial peptides is traditionally attributed to the formation
of pores in the lipid cell membranes of pathogens, which requires a substantial peptide to …

Effect of antimicrobial peptide on the dynamics of phosphocholine membrane: role of cholesterol and physical state of bilayer

VK Sharma, E Mamontov, DB Anunciado, H O'Neill… - Soft matter, 2015 - pubs.rsc.org
Antimicrobial peptides are universal in all forms of life and are well known for their strong
interaction with the cell membrane. This makes them a popular target for investigation of …

MDANSE: An interactive analysis environment for molecular dynamics simulations

G Goret, B Aoun, E Pellegrini - Journal of chemical information …, 2017 - ACS Publications
The MDANSE software Molecular Dynamics Analysis of Neutron Scattering Experiments
is presented. It is an interactive application for postprocessing molecular dynamics (MD) …

Dynamic landscape in self-assembled surfactant aggregates

VK Sharma, S Mitra, R Mukhopadhyay - Langmuir, 2019 - ACS Publications
A process in which a disordered system of pre-existing molecules generates an organized
structure through specific, local interactions among the molecules themselves is termed …

Surfactant desorption and scission free energies for cylindrical and spherical micelles from umbrella-sampling molecular dynamics simulations

B Wen, B Bai, RG Larson - Journal of Colloid and Interface Science, 2021 - Elsevier
Hypothesis The free energies associated with adsorption/desorption of individual surfactants
from micelles and the fusion/scission of long micelles can be used to estimate the rate …

Interfacial hydration dynamics in cationic micelles using 2D-IR and NMR

VP Roy, KJ Kubarych - The Journal of Physical Chemistry B, 2017 - ACS Publications
Using the thiocyanate anion as a vibrational probe chromophore in conjunction with infrared
and NMR spectroscopy, we find that SCN–strongly associates with the cationic head group …

Effect of α-tocopherol on the microscopic dynamics of dimyristoylphosphatidylcholine membrane

VK Sharma, E Mamontov, M Tyagi… - The Journal of Physical …, 2016 - ACS Publications
Vitamin E behaves as an antioxidant and is well known for its protective properties of the
lipid membrane. The most biologically active form of vitamin E in the human organism is α …

[HTML][HTML] Dioctadecyldimethylammonium bromide, a surfactant model for the cell membrane: Importance of microscopic dynamics

VK Sharma, H Srinivasan, V García Sakai… - Structural Dynamics, 2020 - pubs.aip.org
Cationic lipid membranes have recently attracted huge attention both from a fundamental
point of view and due to their practical applications in drug delivery and gene therapy. The …