[HTML][HTML] Oxidative stress and inflammation in acute and chronic lung injuries

FS Bezerra, M Lanzetti, RT Nesi, AC Nagato, CP Silva… - Antioxidants, 2023 - mdpi.com
Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung
injury can affect several components of the respiratory system, including the airways …

Immunology of asthma and chronic obstructive pulmonary disease

PJ Barnes - Nature Reviews Immunology, 2008 - nature.com
Asthma and chronic obstructive pulmonary disease (COPD) are both obstructive airway
diseases that involve chronic inflammation of the respiratory tract, but the type of …

[HTML][HTML] In vitro evaluation of nanoplastics using human lung epithelial cells, microarray analysis and co-culture model

S Yang, Y Cheng, Z Chen, T Liu, L Yin, Y Pu… - … and environmental safety, 2021 - Elsevier
Nanoplastics, including polystyrene nanoplastics (PS-NPs), are widely existed in the
atmosphere, which can be directly and continuously inhaled into the human body, posing a …

Lung microbiome dynamics in COPD exacerbations

Z Wang, M Bafadhel, K Haldar, A Spivak… - European …, 2016 - Eur Respiratory Soc
Increasing evidence suggests that the lung microbiome plays an important role in chronic
obstructive pulmonary disease (COPD) severity. However, the dynamics of the lung …

Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort

AT Hastie, FJ Martinez, JL Curtis… - The Lancet …, 2017 - thelancet.com
Background Increased concentrations of eosinophils in blood and sputum in chronic
obstructive pulmonary disease (COPD) have been associated with increased frequency of …

Respiratory tract mucin genes and mucin glycoproteins in health and disease

MC Rose, JA Voynow - Physiological reviews, 2006 - journals.physiology.org
This review focuses on the role and regulation of mucin glycoproteins (mucins) in airway
health and disease. Mucins are highly glycosylated macromolecules (≥ 50% carbohydrate …

Colonization by Pneumocystis jirovecii and its role in disease

A Morris, KA Norris - Clinical microbiology reviews, 2012 - Am Soc Microbiol
Although the incidence of Pneumocystis pneumonia (PCP) has decreased since the
introduction of combination antiretroviral therapy, it remains an important cause of disease in …

[HTML][HTML] Experimental animal models for COPD: a methodological review

V Ghorani, MH Boskabady, MR Khazdair… - Tobacco induced …, 2017 - Springer
Introduction Chronic obstructive pulmonary disease (COPD) is a progressive disorder that
makes the breathing difficult and is characterized by pathological conditions ranging from …

Anti-TNFα therapy in inflammatory lung diseases

R Malaviya, JD Laskin, DL Laskin - Pharmacology & therapeutics, 2017 - Elsevier
Increased levels of tumor necrosis factor (TNF) α have been linked to a number of
pulmonary inflammatory diseases including asthma, chronic obstructive pulmonary disease …

Transforming growth factor-β: master regulator of the respiratory system in health and disease

Y Aschner, GP Downey - American journal of respiratory cell and …, 2016 - atsjournals.org
In this article, we review the biology and physiological importance of transforming growth
factor-β (TGF-β) to homeostasis in the respiratory system, its importance to innate and …