[HTML][HTML] Pathogenesis of multiple organ injury in COVID-19 and potential therapeutic strategies
Severe acute respiratory disease coronavirus 2 (SARS-CoV-2, formerly 2019-nCoV) is a
novel coronavirus that has rapidly disseminated worldwide, causing the coronavirus disease …
novel coronavirus that has rapidly disseminated worldwide, causing the coronavirus disease …
A review of potential suggested drugs for coronavirus disease (COVID-19) treatment
The latest pandemic, coronavirus disease-2019 (COVID-19), is associated with high
prevalence and easy transmission, which is expanding globally with no conventional …
prevalence and easy transmission, which is expanding globally with no conventional …
Interleukin-6 receptor antagonists in critically ill patients with Covid-19–preliminary report
Remap-Cap Investigators, AC Gordon, PR Mouncey… - Medrxiv, 2021 - medrxiv.org
Background The efficacy of interleukin-6 receptor antagonists in critically ill patients with
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …
Infectious Diseases Society of America Guidelines on the treatment and management of patients with coronavirus disease 2019 (COVID-19)
Background There are many pharmacologic therapies that are being used or considered for
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …
Interleukin-6 receptor antagonists in critically ill patients with Covid-19
Remap-Cap Investigators - New England Journal of Medicine, 2021 - Mass Medical Soc
Background The efficacy of interleukin-6 receptor antagonists in critically ill patients with
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …
The role of IL-6 and IL-6 blockade in COVID-19
N Potere, A Batticciotto, A Vecchié… - Expert review of …, 2021 - Taylor & Francis
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a
dysregulated hyperinflammatory response. Areas covered Authors review evidence on IL-6 …
dysregulated hyperinflammatory response. Areas covered Authors review evidence on IL-6 …
COVID-19, cytokines, inflammation, and spices: How are they related?
Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …
infections. It is also intimately linked with the progression of COVID-19 disease as well as …
Systematic review and meta-analysis of anakinra, sarilumab, siltuximab and tocilizumab for COVID-19
Background There is accumulating evidence for an overly activated immune response in
severe COVID-19, with several studies exploring the therapeutic role of immunomodulation …
severe COVID-19, with several studies exploring the therapeutic role of immunomodulation …
[HTML][HTML] The role of Interleukin 6 inhibitors in therapy of severe COVID-19
E Nasonov, M Samsonov - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Cytokine storm syndrome (CSS) is a severe complication of inflammatory immune diseases
or treatment of malignancies; it may also appear during the progression of COVID-19. CSS …
or treatment of malignancies; it may also appear during the progression of COVID-19. CSS …
Variants in ACE2; potential influences on virus infection and COVID-19 severity
The third pandemic of coronavirus infection, called COVID-19 disease, was first detected in
November 2019th. Various determinants of disease progression such as age, sex, virus …
November 2019th. Various determinants of disease progression such as age, sex, virus …