Candesartan and epigallocatechin‐3‐gallate ameliorate gentamicin‐induced renal damage in rats through p38‐MAPK and NF‐κB pathways
HI Ahmed, EA Mohamed - Journal of biochemical and …, 2019 - Wiley Online Library
This study pointed to estimate the possible protective impacts of candesartan and/or
epigallocatechin‐3‐gallate (EGCG) against gentamicin‐induced nephrotoxicity. The current …
epigallocatechin‐3‐gallate (EGCG) against gentamicin‐induced nephrotoxicity. The current …
Inhibiting renin angiotensin system in rate limiting step by aliskiren as a new approach for preventing indomethacin induced gastric ulcers
Purpose Previously blocking the renin angiotensin system (RAAS) has been effective in the
prevention of gastric damage. Therefore, the aim of this study was to investigate the effects …
prevention of gastric damage. Therefore, the aim of this study was to investigate the effects …
[HTML][HTML] Angiotensin II type 1 receptor blockade suppresses light-induced neural damage in the mouse retina
T Narimatsu, Y Ozawa, S Miyake, N Nagai… - Free Radical Biology and …, 2014 - Elsevier
Exposure to light contributes to the development and progression of retinal degenerative
diseases. However, the mechanisms underlying light-induced tissue damage are not fully …
diseases. However, the mechanisms underlying light-induced tissue damage are not fully …
[PDF][PDF] Targeting oxidative stress and inflammation in NSAIDs induced gastropathy: a plausible therapeutic approach
Deregulation in prostaglandin (PG) biosynthesis, oxidative stress, inflammation, and
apoptosis play a major role in the pathogenesis of nonsteroidal anti-inflammatory drug …
apoptosis play a major role in the pathogenesis of nonsteroidal anti-inflammatory drug …
Duloxetine protected indomethacin-induced gastric mucosal injury by increasing serotonin-dependent RANTES expression and activating PI3K-AKT-VEGF pathway
H Ding, Y Wang, Y Gao, F Ye, K Yao, L Cao… - Toxicology and Applied …, 2024 - Elsevier
Antidepressant duloxetine has been shown protective effect on indomethacin-induced
gastric ulcer, which was escorted by inflammation in the gastric mucosa. Cytokines are the …
gastric ulcer, which was escorted by inflammation in the gastric mucosa. Cytokines are the …
Gastroprotective Activity of the Total Flavones from Abelmoschus manihot (L.) Medic Flowers
J Zhang, ZL Fu, ZX Chu… - … Based Complementary and …, 2020 - Wiley Online Library
Background. Abelmoschus manihot (L.) Medic flower is a medicinal plant for the treatment of
diseases in China. The present study was carried out to scientifically validate the …
diseases in China. The present study was carried out to scientifically validate the …
Molecular Mechanisms of Clozapine-Induced Pancreatic Damage and its Modulation by L-Carnitine in a Rat Model
DIA Mesallam, E Ahmed Alaa El-Din… - Egyptian Society of …, 2024 - journals.ekb.eg
Background: Clozapine (CLZ) has been considered the mainstay drug in treatment of
resistant schizophrenia. Diabetes mellitus has befallen during clozapine therapy. L-carnitine …
resistant schizophrenia. Diabetes mellitus has befallen during clozapine therapy. L-carnitine …
Gastroprotective effects of Taraxacum officinale (Dandelion) extract indomethacin-induced gastric ulcer model
U Hamit, GA USLU - GSC Biological and Pharmaceutical …, 2022 - gsconlinepress.com
In this study, it was aimed to investigate the gastroprotective and anti-inflammatory effects of
the extract (TO) obtain from the leaves of Taraxacum officinale, which is used in the …
the extract (TO) obtain from the leaves of Taraxacum officinale, which is used in the …
Efficacy of olmesartan, irbesartan and telmisartan against acute indomethacin-induced gastric ulcers in mice
S Khallouf, R Makhous, R Issa - Bulletin of Pharmaceutical Sciences …, 2022 - journals.ekb.eg
Recent studies have determined detrimental effects of angiotensin-II in gastric mucosa. This
study aims to investigate the gastroprotective role of some Angiotensin-II receptor blockers …
study aims to investigate the gastroprotective role of some Angiotensin-II receptor blockers …
NSAIDs 肠病时肠道防御素变化对肠道炎症反应的影响
杨红静, 车筑平, 李红灵, 李林俊, 肖源, 谭庆华 - 实用医学杂志, 2014 - cqvip.com
目的: 探讨大鼠NSAIDs 肠病时肠道防御素变化对肠道炎症反应的影响. 方法: 34 只SD
大鼠随机分为模型组及对照组, 每组17 只. 免疫组化检测回肠组织r AD-5, r AD-6 的IOD 值 …
大鼠随机分为模型组及对照组, 每组17 只. 免疫组化检测回肠组织r AD-5, r AD-6 的IOD 值 …