Spirocyclic compounds fascinate the synthetic chemists due to their privileged ring system
and efficacy in drug discovery. Many natural compounds comprise spirocyclic moiety in their …

The review covers the results of studies published in the literature on the synthesis of spiro‐
linked heterocycles of the indole, quinoline, benzoxazine, benzothiazine …

An efficient method to construct unique spiro [indoline-3, 4′-pyrrolo [3, 4-b] pyridines] was
successfully developed via a DABCO promoted formal [3+ 3] cycloaddition reaction of MBH …

Isatin has been utilized in many heterocyclic preparations and considered as an important
building block in organic synthesis. There is a wide range of multi-component reactions that …

Among isatin-based heterocyclic, spirooxindoles are interesting synthetic molecules
because of their variety of pharmacological activities. There is a wide range of multi …

Here, we have described the synthesis of novel spiropyridineoxindole derivatives containing
a pyridone ring via a four-component reaction between various diamines, 1, 1-bis …

Functionalized SBA-15 (immobilization of Pd on the modified SBA-15) has been used as an
efficient catalyst for the preparation of spiroindolines by multi-component reactions of isatins …

We have demonstrated three component reaction of isatin, enaminone and ethyl
cyanoacetate leading to sprirooxindole scaffold without catalyst in water. The synthetic …

A series of spiro [indoline‐3, 2′‐[1, 3, 4] oxadiazol]‐2‐ones were prepared from the
reaction of isatin derivatives and hydrazonoyl chlorides through the 1, 3‐dipolar …

The one-pot multicomponent synthesis of benzo [g] imidazo [1, 2-a] quinolone-6, 11-dione
derivatives in good to high yields, from readily available starting materials including …