Peptide retention time prediction

L Moruz, L Käll - Mass spectrometry reviews, 2017 - Wiley Online Library
Most methods for interpreting data from shotgun proteomics experiments are to large degree
dependent on being able to predict properties of peptide‐ions. Often such predicted …

Predictions of peptides' retention times in reversed‐phase liquid chromatography as a new supportive tool to improve protein identification in proteomics

T Bączek, R Kaliszan - Proteomics, 2009 - Wiley Online Library
One of the initial steps of proteomic analysis is peptide separation. However, little
information from RP‐HPLC, employed for peptides separation, is utilized in proteomics …

A feed forward loop enforces YAP/TAZ signaling during tumorigenesis

MK Gill, T Christova, YY Zhang, A Gregorieff… - Nature …, 2018 - nature.com
In most solid tumors, the Hippo pathway is inactivated through poorly understood
mechanisms that result in the activation of the transcriptional regulators, YAP and TAZ. Here …

Compendium of Chromatographic Behavior of Post-translationally and Chemically Modified Peptides in Bottom-Up Proteomic Experiments

Q Neale, A Prefontaine, T Battellino, B Mizero… - Analytical …, 2023 - ACS Publications
We have systematically evaluated the chromatographic behavior of post-translationally/
chemically modified peptides using data spanning over 70 of the most relevant …

Chromatographic retention time prediction for posttranslationally modified peptides

L Moruz, A Staes, JM Foster, M Hatzou… - …, 2012 - Wiley Online Library
Retention time prediction of peptides in liquid chromatography has proven to be a valuable
tool for mass spectrometry‐based proteomics, especially in designing more efficient …

Deep intact proteoform characterization in human cell lysate using high-pH and low-pH reversed-phase liquid chromatography

D Yu, Z Wang, KA Cupp-Sutton, X Liu… - Journal of the American …, 2019 - ACS Publications
Post-translational modifications (PTMs) play critical roles in biological processes and have
significant effects on the structures and dynamics of proteins. Top-down proteomics methods …

Predictive chromatography of peptides and proteins as a complementary tool for proteomics

IA Tarasova, CD Masselon, AV Gorshkov… - Analyst, 2016 - pubs.rsc.org
In the last couple of decades, considerable effort has been focused on developing methods
for quantitative and qualitative proteome characterization. The method of choice in this …

Retention time prediction for post-translationally modified peptides: Ser, Thr, Tyr-phosphorylation

T Battellino, D Yeung, H Neustaeter, V Spicer… - … of Chromatography A, 2024 - Elsevier
The development of a peptide retention prediction model for reversed-phase
chromatography applications in proteomics is reported for peptides carrying phosphorylated …

An informatics-assisted label-free quantitation strategy that depicts phosphoproteomic profiles in lung cancer cell invasion

YT Wang, CF Tsai, TC Hong, CC Tsou… - Journal of proteome …, 2010 - ACS Publications
Aberrant protein phosphorylation plays important roles in cancer-related cell signaling. With
the goal of achieving multiplexed, comprehensive, and fully automated relative quantitation …

[图书][B] Advances in Chromatography: Volume 45

E Grushka, N Grinberg - 2006 - taylorfrancis.com
For more than four decades, scientists and researchers have relied on the Advances in
Chromatography series for the most up-to-date information on a wide range of …