Is food addictive? A review of the science

AN Gearhardt, EM Schulte - Annual Review of Nutrition, 2021 - annualreviews.org
As ultraprocessed foods (ie, foods composed of mostly cheap industrial sources of dietary
energy and nutrients plus additives) have become more abundant in our food supply, rates …

[HTML][HTML] Stress-induced plasticity and functioning of ventral tegmental dopamine neurons

EH Douma, ER de Kloet - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
The ventral tegmental area dopamine (VTA-DA) mesolimbic circuit processes emotional,
motivational, and social reward associations together with their more demanding cognitive …

Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches

JF Poulin, G Caronia, C Hofer, Q Cui, B Helm… - Nature …, 2018 - nature.com
Midbrain dopamine (DA) neurons have diverse functions that can in part be explained by
their heterogeneity. Although molecularly distinct subtypes of DA neurons have been …

A genetically encoded sensor for in vivo imaging of orexin neuropeptides

L Duffet, S Kosar, M Panniello, B Viberti, E Bracey… - Nature …, 2022 - nature.com
Orexins (also called hypocretins) are hypothalamic neuropeptides that carry out essential
functions in the central nervous system; however, little is known about their release and …

The neurobiological basis of narcolepsy

CE Mahoney, A Cogswell, IJ Koralnik… - Nature Reviews …, 2019 - nature.com
Narcolepsy is the most common neurological cause of chronic sleepiness. The discovery
about 20 years ago that narcolepsy is caused by selective loss of the neurons producing …

Parallel circuits from the bed nuclei of stria terminalis to the lateral hypothalamus drive opposing emotional states

WJ Giardino, A Eban-Rothschild, DJ Christoffel… - Nature …, 2018 - nature.com
Lateral hypothalamus (LH) neurons containing the neuropeptide hypocretin (HCRT; orexin)
modulate affective components of arousal, but their relevant synaptic inputs remain poorly …

Increased number and activity of a lateral subpopulation of hypothalamic orexin/hypocretin neurons underlies the expression of an addicted state in rats

MH James, CM Stopper, BA Zimmer, NE Koll… - Biological …, 2019 - Elsevier
Background The orexin (hypocretin) system is important for reward-driven motivation but has
not been implicated in the expression of a multiphenotype addicted state. Methods Rats …

The hypocretin (orexin) system: from a neural circuitry perspective

SB Li, L de Lecea - Neuropharmacology, 2020 - Elsevier
Hypocretin/orexin neurons are distributed restrictively in the hypothalamus, a brain region
known to orchestrate diverse functions including sleep, reward processing, food intake …

To eat or to sleep: That is a lateral hypothalamic question

E Arrigoni, MJS Chee, PM Fuller - Neuropharmacology, 2019 - Elsevier
The lateral hypothalamus (LH) is a functionally and anatomically complex brain region that
is involved in the regulation of many behavioral and physiological processes including …

A VTA to basal amygdala dopamine projection contributes to signal salient somatosensory events during fear learning

W Tang, O Kochubey, M Kintscher… - Journal of …, 2020 - Soc Neuroscience
The amygdala is a brain area critical for the formation of fear memories. However, the nature
of the teaching signal (s) that drive plasticity in the amygdala are still under debate. Here, we …