Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics

X Li, Y Gao, H Li, JP Majoral, X Shi, A Pich - Progress in Materials Science, 2023 - Elsevier
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …

Engineering functional polymer capsules toward smart nanoreactors

J Gaitzsch, X Huang, B Voit - Chemical reviews, 2016 - ACS Publications
The design and construction of integrated chemical ensembles for studying complex
biological systems is attracting considerable interest in a wide range of research …

Targeted and equally distributed delivery of mrna to organs with pentaerythritol-based one-component ionizable amphiphilic janus dendrimers

J Lu, EN Atochina-Vasserman, DS Maurya… - Journal of the …, 2023 - ACS Publications
Delivery of nucleic acids with viral and synthetic vectors has pioneered genetic
nanomedicine. Four-component lipid nanoparticles (LNPs) consisting of ionizable lipids …

One-component multifunctional sequence-defined ionizable amphiphilic Janus dendrimer delivery systems for mRNA

D Zhang, EN Atochina-Vasserman… - Journal of the …, 2021 - ACS Publications
Efficient viral or nonviral delivery of nucleic acids is the key step of genetic nanomedicine.
Both viral and synthetic vectors have been successfully employed for genetic delivery with …

A systematic framework and nanoperiodic concept for unifying nanoscience: Hard/soft nanoelements, superatoms, meta-atoms, new emerging properties, periodic …

DA Tomalia, SN Khanna - Chemical reviews, 2016 - ACS Publications
Development of a central paradigm is undoubtedly the single most influential force
responsible for advancing Dalton's 19th century atomic/molecular chemistry concepts to the …

Supramolecular architectures of dendritic amphiphiles in water

BNS Thota, LH Urner, R Haag - Chemical reviews, 2016 - ACS Publications
Dendritic molecules are an exciting research topic because of their highly branched
architecture, multiple functional groups on the periphery, and very pertinent features for …

Mimicking complex biological membranes and their programmable glycan ligands with dendrimersomes and glycodendrimersomes

SE Sherman, Q Xiao, V Percec - Chemical reviews, 2017 - ACS Publications
Synthetic vesicles have been assembled and coassembled from phospholipids, their
modified versions, and other single amphiphiles into liposomes, and from block copolymers …

Precision self-assembly of amphiphilic random copolymers into uniform and self-sorting nanocompartments in water

Y Hirai, T Terashima, M Takenaka… - Macromolecules, 2016 - ACS Publications
Self-assembly of amphiphilic molecules in water is a cornerstone to build
compartmentalized materials toward unique functions, whereas it is yet challenging to create …

Recent advances in click chemistry applied to dendrimer synthesis

M Arseneault, C Wafer, JF Morin - Molecules, 2015 - mdpi.com
Dendrimers are monodisperse polymers grown in a fractal manner from a central point. They
are poised to become the cornerstone of nanoscale devices in several fields, ranging from …

Janus particles: from synthesis to application

E Poggi, JF Gohy - Colloid and Polymer Science, 2017 - Springer
Janus particles have built momentum in the last years owing to their unique structure and
properties. In this review, we present an overview of the advances in the field of non …