Thermosensitive hydrogels as scaffolds for cartilage tissue engineering

Y Zhang, J Yu, K Ren, J Zuo, J Ding… - Biomacromolecules, 2019 - ACS Publications
Articular cartilage defects, caused by trauma, osteoarthritis, or other diseases, always lead to
severe joint pain and joint dysfunction. Without access to progenitor cells and the supply of …

How smart do biomaterials need to be? A translational science and clinical point of view

BM Holzapfel, JC Reichert, JT Schantz… - Advanced drug delivery …, 2013 - Elsevier
Over the last 4 decades innovations in biomaterials and medical technology have had a
sustainable impact on the development of biopolymers, titanium/stainless steel and …

Effect of leukocyte concentration on the efficacy of platelet-rich plasma in the treatment of knee osteoarthritis

JC Riboh, BM Saltzman, AB Yanke… - … American journal of …, 2016 - journals.sagepub.com
Background: Leukocyte-poor platelet-rich plasma (LP-PRP) is hypothesized to be more
suitable for intra-articular injection than leukocyte-rich PRP (LR-PRP) in the treatment of …

Platelet-rich plasma intra-articular injection versus hyaluronic acid viscosupplementation as treatments for cartilage pathology: from early degeneration to …

E Kon, B Mandelbaum, R Buda, G Filardo… - … : The Journal of …, 2011 - Elsevier
PURPOSE: The aim of our study is to compare the efficacy of platelet-rich plasma (PRP) and
viscosupplementation (hyaluronic acid [HA]) intra-articular injections for the treatment of …

Collagen scaffolds in cartilage tissue engineering and relevant approaches for future development

V Irawan, TC Sung, A Higuchi, T Ikoma - Tissue engineering and …, 2018 - Springer
Background: Cartilage tissue engineering (CTE) aims to obtain a structure mimicking native
cartilage tissue through the combination of relevant cells, three-dimensional scaffolds, and …

Platelet-rich plasma: intra-articular knee injections produced favorable results on degenerative cartilage lesions

E Kon, R Buda, G Filardo, A Di Martino… - Knee Surgery, Sports …, 2010 - Springer
Platelet-rich plasma (PRP) is a natural concentrate of autologous blood growth factors
experimented in different fields of medicine in order to test its potential to enhance tissue …

Cartilage tissue engineering: molecular control of chondrocyte differentiation for proper cartilage matrix reconstruction

M Demoor, D Ollitrault, T Gomez-Leduc… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Background Articular cartilage defects are a veritable therapeutic problem because
therapeutic options are very scarce. Due to the poor self-regeneration capacity of cartilage …

The efficacy of platelet-rich plasma in the treatment of symptomatic knee osteoarthritis: a systematic review with quantitative synthesis

A Khoshbin, T Leroux, D Wasserstein, P Marks… - … : The Journal of …, 2013 - Elsevier
Purpose The purpose of this systematic review was to synthesize the available Level I and
Level II literature on platelet-rich plasma (PRP) as a therapeutic intervention in the …

Clinical update: why PRP should be your first choice for injection therapy in treating osteoarthritis of the knee

CS Cook, PA Smith - Current reviews in musculoskeletal medicine, 2018 - Springer
Abstract Purpose of Review The purpose of this review is to update the reader on the current
applications of platelet-rich plasma (PRP) in the treatment of knee osteoarthritis (KOA). This …

3D bioprinting of structural proteins

MK Włodarczyk-Biegun, A Del Campo - Biomaterials, 2017 - Elsevier
Abstract 3D bioprinting is a booming method to obtain scaffolds of different materials with
predesigned and customized morphologies and geometries. In this review we focus on the …