Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an
immunoglobulin E (IgE)-mediated inflammation of the membranes lining the nose (1). It was …

■ Abstract The development of allergic rhinitis entails a complex interaction between
genetic predisposition and environmental exposure to different factors, of which the most …

BACKGROUND: Allergic rhinitis represents a global health problem affecting 10% to 20% of
the population. The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines have been …

Leukotrienes (LT) are biologically active lipid mediators known to be involved in allergic
inflammation. Leukotrienes have been shown to mediate diverse features of allergic …

Background To date, genetic studies of hypersensitivity reactions to non‐steroidal anti‐
inflammatory drugs (NSAID s) have been carried out mainly in aspirin‐induced asthma and …

BACKGROUND: Th17 cell lineage, a distinct pro-inflammatory lineage characterized by
preferential synthesis of cytokines IL-17A and IL-17F, is thought to play an important role in …

Background Chronic rhinosinusitis (CRS) is increasingly viewed as an inflammatory
condition of the sinonasal mucosa interacting with bacteria and/or fungi. However, factors …

We introduce the reader to systems biology, using adverse drug reactions (ADRs),
specifically hypersensitivity reactions to multiple non-steroidal anti-inflammatory drugs …

To cite this article: Bunyavanich S, Shargorodsky J, Celedón JC. A meta‐analysis of Th2
pathway genetic variants and risk for allergic rhinitis. Pediatric Allergy Immunology 2011; 22 …

Allergic rhinitis is one of the most common diseases of the upper respiratory system, which
imposes a high cost on countries every year due to its high prevalence. This disease is a …