The immunology of long COVID
DM Altmann, EM Whettlock, S Liu… - Nature Reviews …, 2023 - nature.com
Long COVID is the patient-coined term for the disease entity whereby persistent symptoms
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic …
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic …
Pathogenesis underlying neurological manifestations of long COVID syndrome and potential therapeutics
The development of long-term symptoms of coronavirus disease 2019 (COVID-19) more
than four weeks after primary infection, termed “long COVID” or post-acute sequela of …
than four weeks after primary infection, termed “long COVID” or post-acute sequela of …
Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment
C Greene, R Connolly, D Brennan, A Laffan… - Nature …, 2024 - nature.com
Vascular disruption has been implicated in coronavirus disease 2019 (COVID-19)
pathogenesis and may predispose to the neurological sequelae associated with long …
pathogenesis and may predispose to the neurological sequelae associated with long …
SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice
FL Fontes-Dantas, GG Fernandes, EG Gutman… - Cell reports, 2023 - cell.com
Cognitive dysfunction is often reported in patients with post-coronavirus disease 2019
(COVID-19) syndrome, but its underlying mechanisms are not completely understood …
(COVID-19) syndrome, but its underlying mechanisms are not completely understood …
Role of SARS-CoV-2 spike-protein-induced activation of microglia and mast cells in the pathogenesis of neuro-COVID
TC Theoharides, D Kempuraj - Cells, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). About 45% of COVID-19 patients experience several symptoms a …
disease 2019 (COVID-19). About 45% of COVID-19 patients experience several symptoms a …
Neurological disorders after severe pneumonia are associated with translocation of endogenous bacteria from the lung to the brain
Neurological disorders are a common feature in patients who recover from severe acute
pneumonia. However, the underlying mechanisms remain poorly understood. Here, we …
pneumonia. However, the underlying mechanisms remain poorly understood. Here, we …
Laboratory findings and biomarkers in Long COVID: what do we know so far? Insights into epidemiology, pathogenesis, therapeutic perspectives and challenges
D Tsilingiris, NG Vallianou, I Karampela… - International Journal of …, 2023 - mdpi.com
Long COVID (LC) encompasses a constellation of long-term symptoms experienced by at
least 10% of people after the initial SARS-CoV-2 infection, and so far it has affected about 65 …
least 10% of people after the initial SARS-CoV-2 infection, and so far it has affected about 65 …
Post-SARS-CoV-2 infection and post-vaccine-related neurological complications share clinical features and the same positivity to anti-ACE2 antibodies
M Bellucci, FM Bozzano, C Castellano… - Frontiers in …, 2024 - frontiersin.org
Introduction A potential overlap in symptoms between post-acute COVID-19 syndrome and
post-COVID-19 vaccination syndrome has been noted. We report a paired description of …
post-COVID-19 vaccination syndrome has been noted. We report a paired description of …
[HTML][HTML] Cortical thickness alterations and systemic inflammation define long-COVID patients with cognitive impairment
B Besteher, T Rocktäschel, AP Garza… - Brain, Behavior, and …, 2024 - Elsevier
As the heterogeneity of symptoms is increasingly recognized among long-COVID patients, it
appears highly relevant to study potential pathophysiological differences along the different …
appears highly relevant to study potential pathophysiological differences along the different …
Multifactorial white matter damage in the acute phase and pre-existing conditions may drive cognitive dysfunction after SARS-CoV-2 infection: neuropathology-based …
E Gelpi, S Klotz, M Beyerle, S Wischnewski, V Harter… - Viruses, 2023 - mdpi.com
Background: There is an urgent need to better understand the mechanisms underlying acute
and long-term neurological symptoms after COVID-19. Neuropathological studies can …
and long-term neurological symptoms after COVID-19. Neuropathological studies can …