Materials engineering strategies for cancer vaccine adjuvant development

X Zhang, B Yang, Q Ni, X Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …

mRNA Cancer vaccines: construction and boosting strategies

X Liu, P Huang, R Yang, H Deng - ACS nano, 2023 - ACS Publications
In late 2020, the US Food and Drug Administration (FDA) approved a lipid-based mRNA
vaccine for the prevention of COVID-19, which has pushed this field to be more closely …

Acid‐ionizable iron nanoadjuvant augments STING activation for personalized vaccination immunotherapy of cancer

F Chen, T Li, H Zhang, M Saeed, X Liu… - Advanced …, 2023 - Wiley Online Library
The critical challenge for cancer vaccine‐induced T‐cell immunity is the sustained activation
of antigen cross‐presentation in antigen‐presenting cells (APCs) with innate immune …

Interdisciplinary‐inspired smart antibacterial materials and their biomedical applications

Y Wu, P Liu, B Mehrjou, PK Chu - Advanced Materials, 2024 - Wiley Online Library
The discovery of antibiotics has saved millions of lives, but the emergence of antibiotic‐
resistant bacteria has become another problem in modern medicine. To avoid or reduce the …

IL-7: A promising adjuvant ensuring effective T cell responses and memory in combination with cancer vaccines?

Y Zhao, K Wei, H Chi, Z Xia, X Li - Frontiers in Immunology, 2022 - frontiersin.org
Cancer vaccines exhibit specificity, effectiveness, and safety as an alternative
immunotherapeutic strategy to struggle against malignant diseases, especially with the rapid …

Theranostic nanoparticles with disease-specific administration strategies

P Zhang, Y Li, W Tang, J Zhao, L Jing, KJ McHugh - Nano Today, 2022 - Elsevier
Recent advances in the synthesis of nanomaterials with diagnostic and therapeutic
capabilities have been rapidly reshaping the landscape of precision medicine. Impressive …

Biomimetic and bioinspired nano‐platforms for cancer vaccine development

C Feng, P Tan, G Nie, M Zhu - Exploration, 2023 - Wiley Online Library
The advent of immunotherapy has revolutionized the treating modalities of cancer. Cancer
vaccine, aiming to harness the host immune system to induce a tumor‐specific killing effect …

Mannan-decorated pathogen-like polymeric nanoparticles as nanovaccine carriers for eliciting superior anticancer immunity

Y Xu, S Ma, J Zhao, H Chen, X Si, Z Huang, Z Yu… - Biomaterials, 2022 - Elsevier
Using nanotechnology for cancer vaccine design holds great promise because of the
intrinsic feature of nanoparticles in being captured by antigen-presenting cells (APCs) …

Advanced biomaterials for cell‐specific modulation and restore of cancer immunotherapy

S Ruan, Y Huang, M He, H Gao - Advanced Science, 2022 - Wiley Online Library
The past decade has witnessed the explosive development of cancer immunotherapies.
Nevertheless, low immunogenicity, limited specificity, poor delivery efficiency, and off‐target …

Glucosylated nanovaccines for dendritic cell-targeted antigen delivery and amplified cancer immunotherapy

J Liu, Y Cui, H Cabral, A Tong, Q Yue, L Zhao, X Sun… - ACS …, 2024 - ACS Publications
Engineering nanovaccines capable of targeting dendritic cells (DCs) is desperately required
to maximize antigen cross-presentation to effector immune cells, elicit strong immune …