Nanomaterial-based drug delivery systems for pain treatment and relief: from the delivery of a single drug to co-delivery of multiple therapeutics
Y Xu, X Dong, H Xu, P Jiao, LX Zhao, G Su - Pharmaceutics, 2023 - mdpi.com
The use of nanomaterials in drug delivery systems for pain treatment is becoming
increasingly common. This review aims to summarize how nanomaterial-based drug …
increasingly common. This review aims to summarize how nanomaterial-based drug …
Non-alcoholic fatty liver disease combined with rheumatoid arthritis exacerbates liver fibrosis by stimulating co-localization of PTRF and TLR4 in rats
S Zhang, P Zhu, J Yuan, K Cheng, Q Xu… - Frontiers in …, 2023 - frontiersin.org
Rheumatoid arthritis (RA) has a high prevalence in patients with non-alcoholic fatty liver
disease (NAFLD); however, the underlying mechanism is unclear. To address this, our study …
disease (NAFLD); however, the underlying mechanism is unclear. To address this, our study …
Valsartan as a prophylactic treatment against breast cancer development and niche activation: What molecular sequels follow chronic AT-1R blockade?
Aims Transactivation of insulin-growth-factor-receptor (IGF-1R) by angiotensin-II-type-1-
receptor (AT-1R) was only demonstrated in vascular-smooth-muscle cells and has never …
receptor (AT-1R) was only demonstrated in vascular-smooth-muscle cells and has never …
[HTML][HTML] Nicorandil/morphine crosstalk accounts for antinociception and hepatoprotection in hepatic fibrosis in rats: Distinct roles of opioid/cGMP and NO/KATP …
Previous report indicated that nicorandil potentiated morphine antinociception and
attenuated hepatic injury in liver fibrotic rats. Herein, the underlying mechanisms of …
attenuated hepatic injury in liver fibrotic rats. Herein, the underlying mechanisms of …
Nicorandil mitigates arsenic trioxide‐induced lung injury via modulating vital signalling pathways SIRT1/PGC‐1α/TFAM, JAK1/STAT3, and miRNA‐132 expression
BA Abdel‐Wahab, D Zafaar, MS Habeeb… - British Journal of …, 2024 - Wiley Online Library
Abstract Background and Purpose Nicorandil, a selective opener of potassium channels,
used to treat angina, has drawn attention for its potential in mitigating lung injury, positioning …
used to treat angina, has drawn attention for its potential in mitigating lung injury, positioning …
Determination of trace morphine and its metabolites in mouse urine using a TpBD functionalized bivalve magnetic nano-adsorbent
Y Wang, X Chen, W Qian, T Chen, S Zhang… - Analytical …, 2024 - pubs.rsc.org
In this study, a new type of covalent organic framework (TpBD) functionalized bivalved
magnetic microsphere (TpBD-DS MNS) adsorbent was applied for the enrichment and …
magnetic microsphere (TpBD-DS MNS) adsorbent was applied for the enrichment and …
Nicorandil attenuates cognitive impairment after traumatic brain injury via inhibiting oxidative stress and inflammation: Involvement of BDNF and NGF
Y Tu, D Han, Y Liu, D Hong, R Chen - Brain and Behavior, 2024 - Wiley Online Library
Background and purpose Cognitive impairment is a prevalent adverse consequence of
traumatic brain injury (TBI). The neuroprotective effects of nicorandil (N‐(2‐hydroxyethyl) …
traumatic brain injury (TBI). The neuroprotective effects of nicorandil (N‐(2‐hydroxyethyl) …