Targeted liposomes: A nonviral gene delivery system for cancer therapy
MT Luiz, JAP Dutra, LB Tofani, JTC de Araújo… - Pharmaceutics, 2022 - mdpi.com
Cancer is the second most frequent cause of death worldwide, with 28.4 million new cases
expected for 2040. Despite de advances in the treatment, it remains a challenge because of …
expected for 2040. Despite de advances in the treatment, it remains a challenge because of …
Nanoliposomes for doxorubicin delivery: Reversing drug resistance, stimuli-responsive carriers and clinical translation
Cancer is still a major threat to human life that is characterized by abnormal proliferation and
metastasis of cancer cells. Chemotherapy is procedure of using anti-cancer drugs for …
metastasis of cancer cells. Chemotherapy is procedure of using anti-cancer drugs for …
[HTML][HTML] Nano-formulated siRNA-based therapeutic approaches for cancer therapy
D Jain, SK Prajapati, A Jain, R Singhal - Nano Trends, 2023 - Elsevier
RNAi is a remarkable treatment strategy to knock down gene overexpression in a variety of
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …
The role of cryoprotective agents in liposome stabilization and preservation
To improve liposomes' usage as drug delivery vehicles, cryoprotectants can be utilized to
prevent constituent leakage and liposome instability. Cryoprotective agents (CPAs) or …
prevent constituent leakage and liposome instability. Cryoprotective agents (CPAs) or …
Site-specific delivery of cisplatin and paclitaxel mediated by liposomes: A promising approach in cancer chemotherapy
J Zou - Environmental Research, 2023 - Elsevier
The site-specific delivery of drugs, especially anti-cancer drugs has been an interesting field
for researchers and the reason is low accumulation of cytotoxic drugs in cancer cells …
for researchers and the reason is low accumulation of cytotoxic drugs in cancer cells …
Recent advanced lipid-based nanomedicines for overcoming cancer resistance
P Dechbumroong, R Hu… - Cancer Drug …, 2024 - pmc.ncbi.nlm.nih.gov
The increasing prevalence of cancer drug resistance not only critically limits the efficiency of
traditional therapies but also causes relapses or recurrences of cancer. Consequently, there …
traditional therapies but also causes relapses or recurrences of cancer. Consequently, there …
Influence of the Composition of Cationic Liposomes on the Performance of Cargo Immunostimulatory RNA
A Bishani, DM Makarova, EV Shmendel, MA Maslov… - Pharmaceutics, 2023 - mdpi.com
In this study, the impact of different delivery systems on the cytokine-inducing,
antiproliferative, and antitumor activities of short immunostimulatory double-stranded RNA …
antiproliferative, and antitumor activities of short immunostimulatory double-stranded RNA …
Single shot vs. cocktail: a comparison of mono-and combinative application of miRNA-targeted mesyl oligonucleotides for efficient antitumor therapy
S Gaponova, O Patutina, A Sen'kova, E Burakova… - Cancers, 2022 - mdpi.com
Simple Summary Current approaches to the treatment of oncological diseases are still
suffering from a lack of efficiency and selectivity and are accompanied by pronounced non …
suffering from a lack of efficiency and selectivity and are accompanied by pronounced non …
A Novel 3-meta-Pyridine-1,2,4-oxadiazole Derivative of Glycyrrhetinic Acid as a Safe and Promising Candidate for Overcoming P-Glycoprotein-Mediated Multidrug …
AD Moralev, OV Salomatina, IV Chernikov… - ACS …, 2023 - ACS Publications
Given the pharmacophore properties of the nitrogen-containing moiety in the molecular
structure of P-glycoprotein (P-gp) inhibitors, we report the evaluation of the P-gp inhibitory …
structure of P-glycoprotein (P-gp) inhibitors, we report the evaluation of the P-gp inhibitory …
Current advancements in self-assembling nanocarriers-based siRNA delivery for cancer therapy
G Kandasamy, D Maity - Colloids and Surfaces B: Biointerfaces, 2023 - Elsevier
Different therapeutic practices for treating cancers have significantly evolved to compensate
and/or overcome the failures in conventional methodologies. The demonstrated potentiality …
and/or overcome the failures in conventional methodologies. The demonstrated potentiality …