Targeted liposomes: A nonviral gene delivery system for cancer therapy

MT Luiz, JAP Dutra, LB Tofani, JTC de Araújo… - Pharmaceutics, 2022 - mdpi.com
Cancer is the second most frequent cause of death worldwide, with 28.4 million new cases
expected for 2040. Despite de advances in the treatment, it remains a challenge because of …

Nanoliposomes for doxorubicin delivery: Reversing drug resistance, stimuli-responsive carriers and clinical translation

M Hashemi, F Ghadyani, S Hasani, Y Olyaee… - Journal of Drug Delivery …, 2023 - Elsevier
Cancer is still a major threat to human life that is characterized by abnormal proliferation and
metastasis of cancer cells. Chemotherapy is procedure of using anti-cancer drugs for …

[HTML][HTML] Nano-formulated siRNA-based therapeutic approaches for cancer therapy

D Jain, SK Prajapati, A Jain, R Singhal - Nano Trends, 2023 - Elsevier
RNAi is a remarkable treatment strategy to knock down gene overexpression in a variety of
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …

The role of cryoprotective agents in liposome stabilization and preservation

GF Boafo, KT Magar, MD Ekpo, W Qian, S Tan… - International journal of …, 2022 - mdpi.com
To improve liposomes' usage as drug delivery vehicles, cryoprotectants can be utilized to
prevent constituent leakage and liposome instability. Cryoprotective agents (CPAs) or …

Site-specific delivery of cisplatin and paclitaxel mediated by liposomes: A promising approach in cancer chemotherapy

J Zou - Environmental Research, 2023 - Elsevier
The site-specific delivery of drugs, especially anti-cancer drugs has been an interesting field
for researchers and the reason is low accumulation of cytotoxic drugs in cancer cells …

Recent advanced lipid-based nanomedicines for overcoming cancer resistance

P Dechbumroong, R Hu… - Cancer Drug …, 2024 - pmc.ncbi.nlm.nih.gov
The increasing prevalence of cancer drug resistance not only critically limits the efficiency of
traditional therapies but also causes relapses or recurrences of cancer. Consequently, there …

Influence of the Composition of Cationic Liposomes on the Performance of Cargo Immunostimulatory RNA

A Bishani, DM Makarova, EV Shmendel, MA Maslov… - Pharmaceutics, 2023 - mdpi.com
In this study, the impact of different delivery systems on the cytokine-inducing,
antiproliferative, and antitumor activities of short immunostimulatory double-stranded RNA …

Single shot vs. cocktail: a comparison of mono-and combinative application of miRNA-targeted mesyl oligonucleotides for efficient antitumor therapy

S Gaponova, O Patutina, A Sen'kova, E Burakova… - Cancers, 2022 - mdpi.com
Simple Summary Current approaches to the treatment of oncological diseases are still
suffering from a lack of efficiency and selectivity and are accompanied by pronounced non …

A Novel 3-meta-Pyridine-1,2,4-oxadiazole Derivative of Glycyrrhetinic Acid as a Safe and Promising Candidate for Overcoming P-Glycoprotein-Mediated Multidrug …

AD Moralev, OV Salomatina, IV Chernikov… - ACS …, 2023 - ACS Publications
Given the pharmacophore properties of the nitrogen-containing moiety in the molecular
structure of P-glycoprotein (P-gp) inhibitors, we report the evaluation of the P-gp inhibitory …

Current advancements in self-assembling nanocarriers-based siRNA delivery for cancer therapy

G Kandasamy, D Maity - Colloids and Surfaces B: Biointerfaces, 2023 - Elsevier
Different therapeutic practices for treating cancers have significantly evolved to compensate
and/or overcome the failures in conventional methodologies. The demonstrated potentiality …