Interaction of two commercial azobenzene food dyes, amaranth and new coccine, with human serum albumin: Biophysical characterization

OA Chaves, RJS Loureiro, A Costa-Tuna… - ACS Food Science & …, 2023 - ACS Publications
Food processing and storage cause natural food color to diminish, leading to the addition of
synthetic dyes by the industry. Unfortunately, these dyes have potential health risks, such as …

Carvacrol protects against carbonyl osmolyte-induced structural modifications and aggregation to serum albumin: Insights from physicochemical and molecular …

S Ahmad, R Nabi, SS Alvi, M Khan, S Khan… - International Journal of …, 2022 - Elsevier
The robust use of osmolytes (ie, polyols and sugars) in the key therapeutic
regimens/formulations has questioned their impact beyond the stability of therapeutic …

Small molecule inhibits BACE1 activity by a dual mechanism confirmed by simulations-based study

F Nabi, O Ahmad, A Fatima, A Ahmad… - Journal of …, 2024 - Taylor & Francis
Alzheimer's disease (AD) is a progressive and largely incurable neurodegenerative disorder
that affects millions of people worldwide. It is characterised by the accumulation of amyloid …

Role of salts and solvents on the defibrillation of food dye “sunset yellow” induced hen egg white lysozyme amyloid fibrils

MJ Hakeem, JM Khan, A Malik, FM Husain… - International Journal of …, 2022 - Elsevier
Several food dyes are known to induce amyloid fibrillation when interacting with proteins.
Here, we studied the role of sunset yellow (SY) in the amyloid fibrillation of hen egg white …

Unraveling the impact of tungsten disulfide quantum dots on human serum albumin conformational dynamics and fibrillation pathways: An integrated multi …

Q Xiao, H Cao, X Tu, C Pan, Y Fang… - International Journal of …, 2024 - Elsevier
Herein, the intricate molecular interplay between human serum albumin (HSA) and tungsten
disulfide quantum dots (WS 2 QDs) was probed using spectroscopic techniques and …

Natural compound plumbagin based inhibition of hIAPP revealed by Markov state models based on MD data along with experimental validations

F Nabi, O Ahmad, A Khan, MN Hassan… - Proteins: Structure …, 2024 - Wiley Online Library
Human islet amyloid polypeptide (amylin or hIAPP) is a 37 residue hormone co‐secreted
with insulin from β cells of the pancreas. In patients suffering from type‐2 diabetes, amylin …

Molecular studies between Chitosan and Graphene Oxide-Chitosan nanocomposites with β-galactosidase: from interaction mechanism to structural and functional …

Z Li, H Wang, S Chen, J Li, C Zheng, Y Liu… - Journal of Molecular …, 2024 - Elsevier
Abstract β-galactosidase is employed in multiple domains, including molecular biology, the
dairy industry, and enzyme engineering. To enhance its applicability, β-galactosidase was …

A Mechanistic Insight into the Structure, Conformational Dynamics, Affinity Profile and Energetics of Metanil Yellow-Serum Protein Complex

MSS Rani, P Gopi, A Yadav, P Sharma, S Singh… - Journal of Molecular …, 2024 - Elsevier
Metanil yellow (MYL) is a toxic azo dye extensively used in food preparations and in textile
industry as major colorant. It affects important biological processes leading to development …

Spectroscopic investigation on the interaction of direct yellow-27 with protein (BSA)

B Bisht, P Dey, AK Singh, S Pant… - … and Applications in …, 2022 - iopscience.iop.org
Abstract Direct yellow 27 (DY-27) interaction with bovine serum albumin (BSA) was
investigated using multi-spectroscopic techniques to understand the toxicity mechanism …

Albumin: Engineering Applications

SO Ebhodaghe - Handbook of Biopolymers, 2023 - Springer
Albumin is one of the most abundant plasma proteins found in recent times to possess
multifunctionality. This chapter reveals the properties and engineering applications of …