Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

Melatonin is a pineal indolamine, allegedly known as a circadian rhythm regulator, and an
antioxidative and immunomodulatory molecule. In both experimental and clinical trials …

Last year melatonin was 60 years old, or at least its discovery was 60 years ago. The
molecule itself may well be almost as old as life itself. So it is time to take yet another …

Organisms have an evolutionarily conserved internal rhythm that helps them anticipate and
adapt to daily changes in the environment. Synchronized to the light–dark cycle with a …

Disturbed circadian rhythms have been a risk factor for type 2 diabetes mellitus (T2DM).
Melatonin is the major chronobiotic hormone regulating both circadian rhythm and glucose …

Circadian rhythms,≈ 24 h oscillations in behavior and physiology, are reflected in all cells of
the body and function to optimize cellular functions and meet environmental challenges …

The circadian system is an intricate molecular network of coordinating circadian clocks that
organize the internal synchrony of the organism in response to the environment. These …

Chronic exposure to light at night, as in shift work, alters biological clocks (chronodisruption),
negatively impacting pregnancy outcome in humans. Actually the interaction of maternal and …

The human body follows a physiological rhythm in response to the day/night cycle which is
synchronized with the circadian rhythm through internal clocks. Most cells in the human …

Melatonin (MLT), secreted during the night by the pineal gland, is an efferent hormonal
signal of the master circadian clock located in the suprachiasmatic nucleus (SCN) …