The pyrimidine scaffold is present in many bioactive drugs; therefore, efficient synthetic
routes that provide shorter reaction times, higher yields, and site-selective reactions are …

The pyrazole nucleus and its reduced forms, pyrazolines and pyrazolidine, are privileged
scaffolds in medicinal chemistry due to their remarkable biological activities. A huge number …

Preparation of α,β-unsaturated trifluoromethylketones and their application in the synthesis of
heterocycles Page 1 Reviews and Accounts ARKIVOC 2011 (i) 246-328 Page 246 ©ARKAT-USA …

Five previously synthesized 4-trifluoromethyl-2-(5-aryl-3-styryl-1H-pyrazol-1yl)-pyrimidines
and six 5-aryl-3-styryl-1-carboxamidino-1H-pyrazole derivatives were screened for their …

Heterocyclization of N-(1-chloro-2,2,2-trifluoroethylidene)carbamates with β-enaminoesters—a
novel synthetic strategy to functionalized trifluoromethylated pyrimidines - ScienceDirect …

Because of the need for more effective and less harmful antifungal therapies, and interest in
the synthesis of new carboximidamides, the goal of this study was to determine the …

This review provides a detailed survey of the present literature data on β-alkoxyvinyl-and β-
enaminocarbonyl compounds as CCC bis-electrophiles in reactions with the common NCN …

O oceano apresenta uma vasta diversidade de espécies, entre elas as algas marinhas, as
quais são usadas principalmente como fonte de alimentos, de produtos industriais e para …

This review deals with general and significant developments in the area of chemistry of
fluorinated pyrimidine, pyrazine and pyridazine. Diazines bearing fluoro or α-fluoroalkyl …

A series of twelve novel 2-(pyrazol-1-yl) pyrimidine derivatives was easily obtained under
ultrasonic conditions by the cyclocondensation reaction of 1-carboxamidino-pyrazoles with 4 …