The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

The acute respiratory distress syndrome (ARDS) is a life-threatening lung condition resulting
from direct and indirect insults to the lung. It is characterized by disruption of the endothelial …

The past several years have seen the accumulation of evidence demonstrating that tissue
injury induced by diverse toxicants is due not only to their direct effects on target tissues but …

Objective: Aspiration of oropharyngeal or gastric contents into the lower respiratory tract is a
common event in critically ill patients and can lead to pneumonia or pneumonitis. Aspiration …

Aspiration pneumonitis and aspiration pneumonia are clinical syndromes caused by
aspiration. These conditions are clinically significant due to their high morbidity and …

The lungs are an important site of host defense. The capillary blood contains an increased
concentration of neutrophils and other leukocytes compared with large vessels, due to the …

Various inflammatory diseases are characterized by tissue infiltration of neutrophils.
Chemokines recruit and activate leukocytes, but neutrophils are traditionally known to be …

Molecular mechanisms of the inflammatory reaction in hypoxia-induced lung injury are not
well defined. Therefore, effects of alveolar hypoxia were studied in rat lungs, exposing rats to …

Idiopathic pulmonary fibrosis (IPF), characterized by progressive worsening of dyspnea and
irreversible decline in lung function, is a chronic and progressive respiratory disease with a …

The role of endogenous NO in the regulation of acute lung injury is not well defined. We
investigated the effects of inducible nitric oxide synthase (iNOS) and endothelial NOS …