Long non-coding RNAs (lncRNAs) play important roles in cancer. They are involved in
chromatin remodeling, as well as transcriptional and post-transcriptional regulation, through …

Over the past decades, research on cancer biology has focused on the involvement of
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …

It is estimated that more than 90% of the mammalian genome is transcribed as non-coding
RNAs. Recent evidences have established that these non-coding transcripts are not junk or …

Renal cell carcinoma (RCC) is a major pathological type of kidney cancer and is one of the
most common malignancies worldwide. The unremarkable symptoms of early stages …

The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …

Discovered in 1993, micoRNAs (miRNAs) are now recognized as one of the major
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …

With the advent of next generation sequencing methods and progress in transcriptome
analysis, it became obvious that the human genome contains much more than just protein …

The androgen receptor (AR) plays a central role in establishing an oncogenic cascade that
drives prostate cancer progression. Some prostate cancers escape androgen dependence …

The long noncoding MALAT1 RNA is upregulated in cancer tissues and its elevated
expression is associated with hyper-proliferation, but the underlying mechanism is poorly …

Mitochondria are composed of many small proteins that control protein synthesis, complex
assembly, metabolism, and ion and reactive oxygen species (ROS) handling. We show that …