Bright side of lignin depolymerization: toward new platform chemicals
Lignin, a major component of lignocellulose, is the largest source of aromatic building blocks
on the planet and harbors great potential to serve as starting material for the production of …
on the planet and harbors great potential to serve as starting material for the production of …
Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases
M Shibuya - The Journal of Biochemistry, 2013 - academic.oup.com
Vascular endothelial growth factors (VEGFs) belong to the platelet-derived growth factor
supergene family, and they play central roles in the regulation of angiogenesis and …
supergene family, and they play central roles in the regulation of angiogenesis and …
[HTML][HTML] Combinatorial epigenetics impact of polyphenols and phytochemicals in cancer prevention and therapy
I Arora, M Sharma, TO Tollefsbol - International journal of molecular …, 2019 - mdpi.com
Polyphenols are potent micronutrients that can be found in large quantities in various food
sources and spices. These compounds, also known as phenolics due to their phenolic …
sources and spices. These compounds, also known as phenolics due to their phenolic …
Lignans and Neolignans: Plant secondary metabolites as a reservoir of biologically active substances
F Zálešák, DJYD Bon, J Pospíšil - Pharmacological Research, 2019 - Elsevier
Lignans and neolignans are plant secondary metabolites derived from the oxidative
coupling of phenylpropanoids. Biological activity of these phenolic compounds ranges from …
coupling of phenylpropanoids. Biological activity of these phenolic compounds ranges from …
[HTML][HTML] Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L
Arctigenin (AR) and its glycoside, arctiin, are two major active ingredients of Arctium lappa L
(A lappa), a popular medicinal herb and health supplement frequently used in Asia. In the …
(A lappa), a popular medicinal herb and health supplement frequently used in Asia. In the …
A review of the pharmacological effects of Arctium lappa (burdock)
YS Chan, LN Cheng, JH Wu, E Chan, YW Kwan… - …, 2011 - Springer
Arctium lappa, commonly known as burdock, is being promoted/recommended as a healthy
and nutritive food in Chinese societies. Burdock has been used therapeutically in Europe …
and nutritive food in Chinese societies. Burdock has been used therapeutically in Europe …
[HTML][HTML] 3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions
C Wenzel, B Riefke, S Gründemann, A Krebs… - Experimental cell …, 2014 - Elsevier
Cancer cells in poorly vascularized tumor regions need to adapt to an unfavorable metabolic
microenvironment. As distance from supplying blood vessels increases, oxygen and nutrient …
microenvironment. As distance from supplying blood vessels increases, oxygen and nutrient …
Metabolic profile of the bioactive compounds of burdock (Arctium lappa) seeds, roots and leaves
In this work the bioactive metabolic profile, the antioxidant activity and total phenolic content
of burdock (Arctium lappa) seeds, leaves and roots were obtained. TEAC values and total …
of burdock (Arctium lappa) seeds, leaves and roots were obtained. TEAC values and total …
In vitro anti-inflammatory effects of arctigenin, a lignan from Arctium lappa L., through inhibition on iNOS pathway
F Zhao, L Wang, K Liu - Journal of ethnopharmacology, 2009 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Arctigenin, a bioactive constituent from dried
seeds of Arctium lappa L.(Compositae) which has been widely used as a Traditional …
seeds of Arctium lappa L.(Compositae) which has been widely used as a Traditional …
HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression
B Philip, K Ito, R Moreno-Sánchez, SJ Ralph - Carcinogenesis, 2013 - academic.oup.com
Hypoxic microenvironments frequently exist in many solid tumours with oxygen levels
fluctuating temporally and spatially from normoxia to hypoxia. The response to hypoxia in …
fluctuating temporally and spatially from normoxia to hypoxia. The response to hypoxia in …