DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …

[HTML][HTML] Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role

KS Crider, TP Yang, RJ Berry, LB Bailey - Advances in nutrition, 2012 - Elsevier
ABSTRACT DNA methylation is an epigenetic modification critical to normal genome
regulation and development. The vitamin folate is a key source of the one carbon group …

Automatic lung cancer detection from CT image using improved deep neural network and ensemble classifier

PM Shakeel, MA Burhanuddin, MI Desa - Neural Computing and …, 2022 - Springer
The development of the computer-aided detection system placed an important role in the
clinical analysis for making the decision about the human disease. Among the various …

Associations with early-life socio-economic position in adult DNA methylation

N Borghol, M Suderman, W McArdle… - International journal …, 2012 - academic.oup.com
Background Disadvantaged socio-economic position (SEP) in childhood is associated with
increased adult mortality and morbidity. We aimed to establish whether childhood SEP was …

[HTML][HTML] Profiling DNA methylation based on next-generation sequencing approaches: new insights and clinical applications

D Barros-Silva, CJ Marques, R Henrique, C Jerónimo - Genes, 2018 - mdpi.com
DNA methylation is an epigenetic modification that plays a pivotal role in regulating gene
expression and, consequently, influences a wide variety of biological processes and …

The signature of maternal rearing in the methylome in rhesus macaque prefrontal cortex and T cells

N Provençal, MJ Suderman, C Guillemin… - Journal of …, 2012 - Soc Neuroscience
Early-life adversity is associated with a broad scope of life-long health and behavioral
disorders. Particularly critical is the role of the mother. A possible mechanism is that these …

[HTML][HTML] Understanding'non-genetic'inheritance: insights from molecular-evolutionary crosstalk

I Adrian-Kalchhauser, SE Sultan, LNS Shama… - Trends in ecology & …, 2020 - cell.com
Understanding the evolutionary and ecological roles of'non-genetic'inheritance (NGI) is
daunting due to the complexity and diversity of epigenetic mechanisms. We draw on insights …

Genome-wide CpG density and DNA methylation analysis method (MeDIP, RRBS, and WGBS) comparisons

D Beck, M Ben Maamar, MK Skinner - Epigenetics, 2022 - Taylor & Francis
Genome-wide DNA methylation analysis is one of the most common epigenetic processes
analysed for genome characterization and differential DNA methylation assessment …

Genomic mapping of 5-hydroxymethylcytosine in the human brain

SG Jin, X Wu, AX Li, GP Pfeifer - Nucleic acids research, 2011 - academic.oup.com
Methylation at the 5-position of cytosine is a well-studied epigenetic pathway. In addition to 5-
methylcytosine (5mC), substantial amounts of 5-hydroxymethylcytosine (5hmC) also referred …

[HTML][HTML] IGWO-IVNet3: DL-based automatic diagnosis of lung nodules using an improved gray wolf optimization and InceptionNet-V3

A Bilal, M Shafiq, F Fang, M Waqar, I Ullah, YY Ghadi… - Sensors, 2022 - mdpi.com
Artificial intelligence plays an essential role in diagnosing lung cancer. Lung cancer is
notoriously difficult to diagnose until it has progressed to a late stage, making it a leading …