Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …

Multiple sclerosis (MS) is the most common neurological immune-mediated disease leading
to disability in young adults. The outcome of the disease is unpredictable, and over time …

1Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute
of Neurology, London, UK; 2National Hospital for Neurology and Neurosurgery, Queen …

Multiple sclerosis (MS) is an autoimmune and chronic inflammatory demyelinating disease
of the central nervous system (CNS), which gives rise to focal lesion in CNS and cause …

Although the detailed pathogenesis of multiple sclerosis (MS) is not completely understood,
a broad range of disease-modifying therapies (DMTs) are available. A common side effect of …

Accurate interpretation of a patient's clinical presentation and radiologic studies,
accompanied by knowledgeable and thoughtful application of the 2017 revised McDonald …

Aging is a significant factor influencing the course of multiple sclerosis (MS). Accelerated
telomere attrition is an indicator of premature biological aging and a potential contributor to …

Objectives: The consequences of polypharmacy (intake of≥ 5 drugs) are diverse, including
drug interactions, rising costs and side effects. Risk groups for polypharmacy are …

Ischemic stroke (IS) is a major cause of death and disability, despite early intervention.
Thrombo-inflammation, the inflammatory process triggered by ischemia, is a concept that …

Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central
nervous system (CNS) that often progresses to severe disability. Previous studies have …