Effects of algae bioactive compounds on Trypanosoma cruzi: A systematic review

YAS Moura, JN da Silva Júnior, VMB de Lorena… - Algal Research, 2021 - Elsevier
Chagas disease (CD) is caused by the protozoan Trypanosoma cruzi which has
trypomastigotes and amastigotes as clinical forms. Several clinical symptoms and …

Assessment of toxicity of Parthenium hysterophorus L. extract against larvae of Trogoderma granarium.

S Ahmad, R Zafar, IH Khan, A Javaid, A Intisar - 2022 - cabidigitallibrary.org
The leaves of parthenium (Parthenium hysterophorus L.) were extracted in ethanol and
toxicity of the extract was examined on khapra beetle (Trogoderma granarium Everts) larvae …

Chemotherapeutic potentials of β‐ionone against Trypanosoma congolense infection: Inhibition of parasite proliferation, anemia development, trans‐sialidase …

S Aminu, MA Ibrahim, G Dada Chechet… - Chemical biology & …, 2022 - Wiley Online Library
Trypanosoma congolense is a pathogenic African animal trypanosome species causing
devastating conditions leading to death of an infected host. The drawbacks of the existing …

Therapeutic efficacy of β-sitosterol treatment on Trypanosoma congolense infection, anemia development, and trans-sialidase (TconTS1) gene expression

S Aminu, GD Chechet, SS Alkhalil, M Sobeh… - Frontiers in …, 2023 - frontiersin.org
Background African animal trypanosomiasis hinders sustainable livestock productivity in sub-
Saharan Africa. About 17 million infected cattle are treated with trypanocides annually but …

Phloroglucinol as a Potential Candidate against Trypanosoma congolense Infection: Insights from In Vivo, In Vitro, Molecular Docking and Molecular Dynamic …

NI Abdulrashid, S Aminu, RM Adamu, N Tajuddeen… - Molecules, 2022 - mdpi.com
Sub-Saharan Africa is profoundly challenged with African Animal Trypanosomiasis and the
available trypanocides are faced with drawbacks, necessitating the search for novel agents …

Phytol suppresses parasitemia and ameliorates anaemia and oxidative brain damage in mice infected with Plasmodium berghei

MA Usman, FI Usman, MS Abubakar, AA Salman… - Experimental …, 2021 - Elsevier
The quest for the development of a novel antimalarial drug informed the decision to subject
phytol to in vivo trials following a demonstration of therapeutic potential against chloroquine …

[HTML][HTML] The activities of suaveolol and other compounds from Hyptis suaveolens and Momordica charantia against the aetiological agents of African trypanosomiasis …

EE Oaikhena, UA Yahaya, SM Abdulsalami… - Experimental …, 2024 - Elsevier
African trypanosomiasis and malaria are among the most severe health challenges to
humans and livestock in Africa and new drugs are needed. Leaves of Hyptis suaveolens …

[HTML][HTML] Possible hemoglobin enhancing effect of phytol in methotrexate-induced folate deficient Swiss albino mice: In vivo and in silico studies

MT Islam, R Chowdhury, MS Al Hasan, S Sheikh… - Pharmaceutical Science …, 2024 - Elsevier
The diterpenoid phytol is evidently acting against anemia in experimental animals. However,
the molecular mechanisms behind this issue are yet to be discovered. This study aimed to …

β-Sitosterol could serve as a dual inhibitor of Trypanosoma congolense sialidase and phospholipase A2: in vitro kinetic analyses and molecular dynamic simulations

S Aminu, AU Danazumi, ZA Alhafiz, MW Gorna… - Molecular Diversity, 2023 - Springer
The involvement of Trypanosoma congolense sialidase alongside phospholipase A2 has
been widely accepted as the major contributing factor to anemia during African animal …

Mitigation of Trypanosoma congolense-Associated Anemia and Expression of Trans-sialidase (TconTS) Gene Variants by Eugenol

A Ibrahim, S Aminu, HC Nzelibe, GD Chechet… - Acta Parasitologica, 2024 - Springer
Abstract Purpose African Animal Trypanosomosis (AAT) caused by Trypanosoma
congolense is a parasitic disease affecting the livestock industry in sub-Saharan Africa and …