Pluripotent stem cell energy metabolism: an update

T Teslaa, MA Teitell - The EMBO journal, 2015 - embopress.org
Recent studies link changes in energy metabolism with the fate of pluripotent stem cells
(PSC s). Safe use of PSC derivatives in regenerative medicine requires an enhanced …

Microfluidics for neuronal cell and circuit engineering

R Habibey, JE Rojo Arias, J Striebel… - Chemical …, 2022 - ACS Publications
The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …

The importance of ubiquitination and deubiquitination in cellular reprogramming

B Suresh, J Lee, KS Kim… - Stem cells …, 2016 - Wiley Online Library
Ubiquitination of core stem cell transcription factors can directly affect stem cell maintenance
and differentiation. Ubiquitination and deubiquitination must occur in a timely and well …

Investigational Rho kinase inhibitors for the treatment of glaucoma

G Al-Humimat, I Marashdeh, D Daradkeh… - Journal of …, 2021 - Taylor & Francis
This review provides a comprehensive update on emerging ROCK inhibitors as an
innovative treatment option for lowering intraocular pressure (IOP) in glaucoma and aims to …

FoxO proteins in the nervous system

K Maiese - Analytical cellular pathology, 2015 - Wiley Online Library
Acute as well as chronic disorders of the nervous system lead to significant morbidity and
mortality for millions of individuals globally. Given the ability to govern stem cell proliferation …

[HTML][HTML] Picking a bone with WISP1 (CCN4): new strategies against degenerative joint disease

K Maiese - Journal of translational science, 2016 - ncbi.nlm.nih.gov
As the world's population continues to age, it is estimated that degenerative joint disease
disorders such as osteoarthritis will impact at least 130 million individuals throughout the …

Reprogramming with small molecules instead of exogenous transcription factors

T Lin, S Wu - Stem cells international, 2015 - Wiley Online Library
Induced pluripotent stem cells (iPSCs) could be employed in the creation of patient‐specific
stem cells, which could subsequently be used in various basic and clinical applications …

WISP1: Clinical insights for a proliferative and restorative member of the CCN family

K Maiese - Current Neurovascular Research, 2014 - ingentaconnect.com
As a proliferative and restorative entity, Wnt1 inducible signaling pathway protein 1 (WISP1)
is emerging as a novel target for a number of therapeutic strategies that are relevant for …

Novel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic disease

K Maiese - Neural regeneration research, 2015 - journals.lww.com
Diabetes mellitus affects almost 350 million individuals throughout the globe resulting in
significant morbidity and mortality. Of further concern is the growing population of individuals …

[HTML][HTML] Forkhead transcription factors: new considerations for alzheimer's disease and dementia

K Maiese - Journal of translational science, 2016 - ncbi.nlm.nih.gov
Life expectancy of individuals in both developed and undeveloped nations continues to rise
at an unprecedented rate. Coupled to this increase in longevity for individuals is the rise in …