Mechanisms underlying the comorbidity of schizophrenia and type 2 diabetes mellitus

Y Mizuki, S Sakamoto, Y Okahisa… - International Journal …, 2021 - academic.oup.com
The mortality rate of patients with schizophrenia is high, and life expectancy is shorter by 10
to 20 years. Metabolic abnormalities including type 2 diabetes mellitus (T2DM) are among …

Socioeconomic deprivation, adverse childhood experiences and medical disorders in adulthood: mechanisms and associations

G Morris, M Berk, M Maes, AF Carvalho, BK Puri - Molecular neurobiology, 2019 - Springer
Severe socioeconomic deprivation (SED) and adverse childhood experiences (ACE) are
significantly associated with the development in adulthood of (i) enhanced inflammatory …

Elevated C-reactive protein, interleukin 6, tumor necrosis factor alpha and glycemic load associated with type 2 diabetes mellitus in rural Thais: a cross-sectional study

C Phosat, P Panprathip, N Chumpathat… - BMC endocrine …, 2017 - Springer
Background The elevated levels of inflammatory markers, including C-reactive protein
(CRP), tumor necrosis factor alpha (TNF-α), and interleukin 6 (IL6) are supposed to be …

Association of tumor necrosis factor alpha, interleukin 6, and C‐reactive protein with the risk of developing type 2 diabetes: a retrospective cohort study of rural thais

J Lainampetch, P Panprathip, C Phosat… - Journal of diabetes …, 2019 - Wiley Online Library
The linkage of obesity, inflammation, and type 2 diabetes mellitus (T2DM) has been
extensively investigated for over a decade. However, the association between inflammatory …

[HTML][HTML] Role of inflammatory mediators (TNF-α, IL-6, CRP), biochemical and hematological parameters in type 2 diabetes mellitus patients of Kashmir, India

H Bashir, SA Bhat, S Majid, R Hamid… - Medical journal of the …, 2020 - ncbi.nlm.nih.gov
Background: Type II Diabetes mellitus (T2DM) is a multifactorial disease and a leading
cause of premature deaths. Inflammatory cytokines are reported that they have potential to …

Pathology, Risk Factors, and Oxidative Damage Related to Type 2 Diabetes‐Mediated Alzheimer's Disease and the Rescuing Effects of the Potent Antioxidant …

MS Khan, M Ikram, TJ Park… - Oxidative medicine and …, 2021 - Wiley Online Library
The pathology and neurodegeneration in type 2 diabetes‐(T2D‐) mediated Alzheimer's
disease (AD) have been reported in several studies. Despite the lack of information …

Cytokines as biomarkers of pancreatic ductal adenocarcinoma: a systematic review

YY Yako, D Kruger, M Smith, M Brand - PloS one, 2016 - journals.plos.org
Objectives A systematic review of the role of cytokines in clinical medicine as diagnostic,
prognostic, or predictive biomarkers in pancreatic ductal adenocarcinoma was undertaken …

Association of IL-10 (− 1082 A/G) and IL-6 (− 174 G/C) gene polymorphism with type 2 diabetes mellitus in Ethiopia population

B Ayelign, M Negash, H Andualem… - BMC endocrine …, 2021 - Springer
Abstract Background Interleukin (IL)-6 and IL-10 are the most important cytokine with pro
and anti-inflammatory activities, respectively. Dysregulation of IL-6 and IL-10 are associated …

Variations in the Obesity Gene “LEPR” Contribute to Risk of Type 2 Diabetes Mellitus: Evidence from a Meta‐Analysis

MM Yang, J Wang, JJ Fan, TK Ng… - Journal of diabetes …, 2016 - Wiley Online Library
Leptin is a hormone protein regulating food intake and energy expenditure. A number of
studies have evaluated the genetic effect of leptin (LEP) and leptin receptor (LEPR) genes …

Overview of transcriptomic research on type 2 diabetes: challenges and perspectives

ZN Tonyan, YA Nasykhova, MM Danilova, YA Barbitoff… - Genes, 2022 - mdpi.com
Type 2 diabetes (T2D) is a common chronic disease whose etiology is known to have a
strong genetic component. Standard genetic approaches, although allowing for the …