[HTML][HTML] Neonatal hypoxia ischaemia: mechanisms, models, and therapeutic challenges
LJ Millar, L Shi, A Hoerder-Suabedissen… - Frontiers in cellular …, 2017 - frontiersin.org
Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …
human neonates, and is often associated with persistent motor, sensory, and cognitive …
[HTML][HTML] Repurposing immunomodulatory drugs to combat tuberculosis
S Fatima, A Bhaskar, VP Dwivedi - Frontiers in Immunology, 2021 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by an obligate intracellular pathogen,
Mycobacterium tuberculosis (M. tb) and is responsible for the maximum number of deaths …
Mycobacterium tuberculosis (M. tb) and is responsible for the maximum number of deaths …
[HTML][HTML] Postnatal infection is associated with widespread abnormalities of brain development in premature newborns
Results: In 34/117 newborns studied, clinical signs were accompanied by positive cultures
whereas 17 had clinical signs of sepsis alone. White matter injury (WMI) was identified in 34 …
whereas 17 had clinical signs of sepsis alone. White matter injury (WMI) was identified in 34 …
Inflammation-initiating illnesses, inflammation-related proteins, and cognitive impairment in extremely preterm infants
TM O'Shea, B Shah, EN Allred, RN Fichorova… - Brain, behavior, and …, 2013 - Elsevier
Neonatal inflammation is associated with perinatal brain damage. We evaluated to what
extent elevated blood levels of inflammation-related proteins supplement information about …
extent elevated blood levels of inflammation-related proteins supplement information about …
A review of immunomodulatory effects of fluoroquinolones
S Assar, R Nosratabadi… - Immunological …, 2021 - Taylor & Francis
Past researches indicate that some types of antibiotics, apart from their antimicrobial effects,
have some other important effects which indirectly are exerted by modulating and regulating …
have some other important effects which indirectly are exerted by modulating and regulating …
[HTML][HTML] Narciclasine improves outcome in sepsis among neonatal rats via inhibition of calprotectin and alleviating inflammatory responses
Sepsis is associated with exacerbated inflammatory response which subsequently results in
multiple organ dysfunction. Sepsis accounts for high mortality and morbidity among …
multiple organ dysfunction. Sepsis accounts for high mortality and morbidity among …
Population pharmacokinetics of ciprofloxacin in neonates and young infants less than three months of age
W Zhao, H Hill, C Le Guellec, T Neal… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Ciprofloxacin is used in neonates with suspected or documented Gram-negative serious
infections. Currently, its use is off-label partly because of lack of pharmacokinetic studies …
infections. Currently, its use is off-label partly because of lack of pharmacokinetic studies …
Effects of neonatal systemic inflammation on blood‐brain barrier permeability and behaviour in juvenile and adult rats
HB Stolp, PA Johansson, MD Habgood… - Cardiovascular …, 2011 - Wiley Online Library
Several neurological disorders have been linked to inflammatory insults suffered during
development. We investigated the effects of neonatal systemic inflammation, induced by …
development. We investigated the effects of neonatal systemic inflammation, induced by …
Bilirubin-induced neural impairment: a special focus on myelination, age-related windows of susceptibility and associated co-morbidities
D Brites, A Fernandes - Seminars in Fetal and Neonatal Medicine, 2015 - Elsevier
Bilirubin-induced neurologic dysfunction (BIND) and classical kernicterus are clinical
manifestations of moderate to severe hyperbilirubinemia whenever bilirubin levels exceed …
manifestations of moderate to severe hyperbilirubinemia whenever bilirubin levels exceed …
Infection‐induced vulnerability of perinatal brain injury
A growing body of evidence demonstrates that susceptibility and progression of both acute
and chronic central nervous system disease in the newborn is closely associated with an …
and chronic central nervous system disease in the newborn is closely associated with an …