[HTML][HTML] Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice
Obesity is a health problem affecting more than 40% of US adults and 13% of the global
population. Anti-obesity treatments including diet, exercise, surgery and pharmacotherapies …
population. Anti-obesity treatments including diet, exercise, surgery and pharmacotherapies …
[HTML][HTML] Cryptococcus neoformans urease affects the outcome of intracellular pathogenesis by modulating phagolysosomal pH
MS Fu, C Coelho, CM De Leon-Rodriguez… - PLoS …, 2018 - journals.plos.org
Cryptococcus neoformans is a facultative intracellular pathogen and its interaction with
macrophages is a key event determining the outcome of infection. Urease is a major …
macrophages is a key event determining the outcome of infection. Urease is a major …
[HTML][HTML] Chronic kidney disease promotes cerebral microhemorrhage formation
Background Chronic kidney disease (CKD) is increasingly recognized as a stroke risk factor,
but its exact relationship with cerebrovascular disease is not well-understood. We …
but its exact relationship with cerebrovascular disease is not well-understood. We …
The effect of size, charge, and peptide ligand length on kidney targeting by small, organic nanoparticles
Chronic kidney disease (CKD) affects 15% of the US adult population. However, most
clinically available drugs for CKD show low bioavailability to the kidneys and non‐specific …
clinically available drugs for CKD show low bioavailability to the kidneys and non‐specific …
Design and in vivo characterization of kidney-targeting multimodal micelles for renal drug delivery
One in three Americans is at risk for developing chronic kidney disease (CKD) and end-
stage renal disease (ESRD), leading to the need for dialysis or a kidney transplant. Small …
stage renal disease (ESRD), leading to the need for dialysis or a kidney transplant. Small …
CCR2-targeted micelles for anti-cancer peptide delivery and immune stimulation
N Trac, LY Chen, A Zhang, CP Liao, C Poon… - Journal of Controlled …, 2021 - Elsevier
Signaling between the Csingle bondC chemokine receptor 2 (CCR2) with its ligand,
monocyte chemoattractant protein-1 (MCP-1) promotes cancer progression by directly …
monocyte chemoattractant protein-1 (MCP-1) promotes cancer progression by directly …
Lactobacillus rhamnosus Reduces Blood Glucose Level through Downregulation of Gluconeogenesis Gene Expression in Streptozotocin‐Induced Diabetic Rats
Some lactic acid bacteria (LAB) are observed to be potential probiotics with functional
properties such as lowering fasting blood glucose (FBG), as a promising hyperglycemia …
properties such as lowering fasting blood glucose (FBG), as a promising hyperglycemia …
[HTML][HTML] Acute and sub-chronic toxicity evaluation of the crude methanolic extract of Diospyros mespiliformis hochst ex a. Dc (ebenaceae) and its fractions
Diospyros mespiliformis, commonly called Jackal berry or African ebony, belongs to the
plant family, Ebenaceae. The roots, barks and leaves have been used traditionally to treat …
plant family, Ebenaceae. The roots, barks and leaves have been used traditionally to treat …
Impact of impaired renal function on gadolinium retention after administration of gadolinium-based contrast agents in a mouse model
AAP Kartamihardja, T Nakajima, S Kameo… - Investigative …, 2016 - journals.lww.com
Objectives The aim of this study was to investigate the impact of impaired renal function on
gadolinium (Gd) retention in various organs after Gd-based contrast agent injection …
gadolinium (Gd) retention in various organs after Gd-based contrast agent injection …
Nickel oxide-deposited cellulose/CNT composite electrode for non-enzymatic urea detection
NS Nguyen, HH Yoon - Sensors and Actuators B: Chemical, 2016 - Elsevier
A highly sensitive non-enzymatic urea sensor was fabricated using nickel oxide deposited
on a cellulose/carbon nanotube (CNT) composite. The structure and morphological …
on a cellulose/carbon nanotube (CNT) composite. The structure and morphological …