Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Background While six US states have already officially authorized cannabinoids to substitute
opioids and treat opioid use disorder, the therapeutic benefits of cannabinoids remain …

A growing body of research has reported on the potential opioid-sparing effects of cannabis
and cannabinoids, but less is known about specific mechanisms. The present research …

This paper is the forty-fourth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Background Individuals with an Opioid Use Disorder (OUD) have increased rates of
cannabis use in comparison to the general population. Research on the short-and long-term …

Objective Patients in treatment with medications for opioid use disorder (MOUD) often report
use of other substances in addition to opioids. Few studies exist that examine the …

Background Cannabis use during methadone treatment may negatively impact treatment
outcomes. The aim of this study was to determine the prevalence and pattern of cannabis …

Despite being illegal under US federal law, cannabis has gained widespread public
acceptance. Over half of US adults (59%) believe that cannabis should be legal for …

Recovery from addiction is frequently equated with abstinence. However, some individuals
who resolve an addiction continue to use substances, including via substitution (ie …

Importance It is known that only minority of patients with opioid use disorder (OUD) receive
treatment, of which only a fraction successfully complete treatment as intended. Factors …