Animal models for SARS‐CoV‐2 research: a comprehensive literature review

K Pandey, A Acharya, M Mohan, CL Ng… - Transboundary and …, 2021 - Wiley Online Library
Emerging and re‐emerging viral diseases can create devastating effects on human lives
and may also lead to economic crises. The ongoing COVID‐19 pandemic due to the novel …

A novel tool to eradicate an ancient scourge: the novel oral polio vaccine type 2 story

AS Bandyopadhyay, S Zipursky - The Lancet Infectious Diseases, 2023 - thelancet.com
The recent detection of vaccine-derived poliovirus (VDPV) in London (UK) and a case of
paralytic polio in New York (USA) have highlighted how the scourge of poliomyelitis has not …

Genetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3

MT Yeh, M Smith, S Carlyle, JL Konopka-Anstadt… - Nature, 2023 - nature.com
Vaccination with Sabin, a live attenuated oral polio vaccine (OPV), results in robust intestinal
and humoral immunity and has been key to controlling poliomyelitis. As with any RNA virus …

Evolving epidemiology of poliovirus serotype 2 following withdrawal of the serotype 2 oral poliovirus vaccine

GR Macklin, KM O'Reilly, NC Grassly, WJ Edmunds… - Science, 2020 - science.org
Although there have been no cases of serotype 2 wild poliovirus for more than 20 years,
transmission of serotype 2 vaccine-derived poliovirus (VDPV2) and associated paralytic …

[PDF][PDF] A defective viral genome strategy elicits broad protective immunity against respiratory viruses

Y Xiao, PV Lidsky, Y Shirogane, R Aviner, CT Wu, W Li… - Cell, 2021 - cell.com
RNA viruses generate defective viral genomes (DVGs) that can interfere with replication of
the parental wild-type virus. To examine their therapeutic potential, we created a DVG by …

Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in children and infants …

X Sáez-Llorens, AS Bandyopadhyay, C Gast… - The Lancet, 2021 - thelancet.com
Background Continued emergence and spread of circulating vaccine-derived type 2
polioviruses and vaccine-associated paralytic poliomyelitis from Sabin oral poliovirus …

Development of a new oral poliovirus vaccine for the eradication end game using codon deoptimization

JL Konopka-Anstadt, R Campagnoli, A Vincent, J Shaw… - npj Vaccines, 2020 - nature.com
Enormous progress has been made in global efforts to eradicate poliovirus, using live-
attenuated Sabin oral poliovirus vaccine (OPV). However, as the incidence of disease due to …

Advances in Toxoplasma gondii Vaccines: Current Strategies and Challenges for Vaccine Development

KB Chu, FS Quan - Vaccines, 2021 - mdpi.com
Toxoplasmosis, caused by the apicomplexan parasite Toxoplasma gondii, is one of the most
damaging parasite-borne zoonotic diseases of global importance. While approximately one …

Engineering antiviral vaccines

X Zhou, X Jiang, M Qu, GE Aninwene, V Jucaud… - ACS …, 2020 - ACS Publications
Despite the vital role of vaccines in fighting viral pathogens, effective vaccines are still
unavailable for many infectious diseases. The importance of vaccines cannot be overstated …

[HTML][HTML] Enabling accelerated vaccine roll-out for public health emergencies of international concern (PHEICs): novel oral polio vaccine type 2 (nOPV2) experience

GR Macklin, C Peak, M Eisenhawer, F Kurji, O Mach… - Vaccine, 2023 - Elsevier
To address the evolving risk of circulating vaccine-derived poliovirus type 2 (cVDPV2),
Global Polio Eradication Initiative (GPEI) partners are working closely with countries to …