Structurally uncommon secondary metabolites derived from endophytic fungi

HE Ortega, D Torres-Mendoza, Z Caballero E… - Journal of Fungi, 2021 - mdpi.com
Among microorganisms, endophytic fungi are the least studied, but they have attracted
attention due to their high biological diversity and ability to produce novel and bioactive …

Bioactive Secondary Metabolites of the Genus Diaporthe and Anamorph Phomopsis from Terrestrial and Marine Habitats and Endophytes: 2010–2019

TC Xu, YH Lu, JF Wang, ZQ Song, YG Hou, SS Liu… - Microorganisms, 2021 - mdpi.com
The genus Diaporthe and its anamorph Phomopsis are distributed worldwide in many
ecosystems. They are regarded as potential sources for producing diverse bioactive …

Cytotoxic Ergosteroids from a Strain of the Fungus Talaromyces adpressus

M Zheng, Y Xiao, Q Li, Y Lai, B Dai… - Journal of Natural …, 2023 - ACS Publications
Nine new ergosteroids (1–9) and seven known ones (10–16) were isolated from
Talaromyces adpressus. Their structures and absolute configurations were determined by …

Endophytic fungi as a source of antiviral compounds–a review

ÍCS Lacerda, JC Polonio, HC Golias - Chemistry & Biodiversity, 2022 - Wiley Online Library
Endophytic fungi are a rich source of secondary metabolites. The interactions between
endophytes and their hosts lead to the production of several bioactive substances grouped …

Bipolarolides A–G: Ophiobolin‐Derived Sesterterpenes with Three New Carbon Skeletons from Bipolaris sp. TJ403‐B1

M Liu, W Sun, L Shen, Y He, J Liu… - Angewandte Chemie …, 2019 - Wiley Online Library
Abstract Bipolarolides A–G (1–7), seven novel ophiobolin‐derived sesterterpenes with three
new types of skeletons, were characterized from fungus Bipolaris sp. TJ403‐B1. Their …

Rearranged ergostane-type natural products: Chemistry, biology, and medicinal aspects

FL Duecker, F Reuß, P Heretsch - Organic & Biomolecular Chemistry, 2019 - pubs.rsc.org
Classical steroids are long-known privileged leads in drug discovery. Their rearranged
counterparts, though, have so far received less attention, although recent isolation and …

Bioactive secondary metabolites from the marine-associated fungus Aspergillus terreus

M Liu, W Sun, J Wang, Y He, J Zhang, F Li, C Qi… - Bioorganic …, 2018 - Elsevier
Three new compounds, including a prenylated tryptophan derivative, luteoride E (1), a
butenolide derivative, versicolactone G (2), and a linear aliphatic alcohol,(3E, 7E)-4, 8 …

Periconiastone A, an Antibacterial Ergosterol with a Pentacyclo[8.7.0.01,5.02,14.010,15]heptadecane System from Periconia sp. TJ403-rc01

W Gao, C Chai, Y He, F Li, X Hao, F Cao, L Gu… - Organic …, 2019 - ACS Publications
Periconiastone A (1), an ergosterol with an unprecedented pentacyclo [8.7. 0.01, 5.02,
14.010, 15] heptadecane system, was isolated from Periconia sp. TJ403-rc01. Its structure …

Structure and biological activity of ergostane-type steroids from fungi

VN Zhabinskii, P Drasar, VA Khripach - Molecules, 2022 - mdpi.com
Mushrooms are known not only for their taste but also for beneficial effects on health
attributed to plethora of constituents. All mushrooms belong to the kingdom of fungi, which …

Spiroaspertrione A, a Bridged Spirocyclic Meroterpenoid, as a Potent Potentiator of Oxacillin against Methicillin-Resistant Staphylococcus aureus from Aspergillus sp …

Y He, Z Hu, W Sun, Q Li, XN Li, H Zhu… - The Journal of …, 2017 - ACS Publications
Bioassay-guided isolation of cultures of Aspergillus sp. TJ23 yielded a novel terpene-
polyketide hybrid spiromeroterpenoid, spiroaspertrione A (1), bearing a unique spiro [bicyclo …