Browning of the white adipose tissue regulation: New insights into nutritional and metabolic relevance in health and diseases

SA Machado, G Pasquarelli-do-Nascimento… - Nutrition & …, 2022 - Springer
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining
health and homeostasis. Although white adipose tissue and brown adipose tissue are …

Cardiac natriuretic peptides

JP Goetze, BG Bruneau, HR Ramos, T Ogawa… - Nature Reviews …, 2020 - nature.com
Investigations into the mixed muscle–secretory phenotype of cardiomyocytes from the atrial
appendages of the heart led to the discovery that these cells produce, in a regulated …

Brown adipose tissue—a translational perspective

AC Carpentier, DP Blondin, F Haman… - Endocrine …, 2023 - academic.oup.com
Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

The role of exercise in the interplay between myokines, hepatokines, osteokines, adipokines, and modulation of inflammation for energy substrate redistribution and …

AM Gonzalez-Gil, L Elizondo-Montemayor - Nutrients, 2020 - mdpi.com
Exercise is an effective strategy for preventing and treating obesity and its related
cardiometabolic disorders, resulting in significant loss of body fat mass, white adipose tissue …

Aerobic exercise promotes the functions of brown adipose tissue in obese mice via a mechanism involving COX2 in the VEGF signaling pathway

P Fu, R Zhu, J Jia, Y Hu, C Wu, P Cieszczyk… - Nutrition & …, 2021 - Springer
Background High-fat diet (HFD)-induced obesity causes immune cells to infiltrate adipose
tissue, leading to chronic inflammation and metabolic syndrome. Brown adipose tissue …

BACE1: More than just a β‐secretase

HA Taylor, L Przemylska, EM Clavane… - Obesity …, 2022 - Wiley Online Library
Summary β‐site amyloid precursor protein cleaving enzyme‐1 (BACE1) research has
historically focused on its actions as the β‐secretase responsible for the production of β …

Anti-obesity effects of metformin: a scoping review evaluating the feasibility of brown adipose tissue as a therapeutic target

K Ziqubu, SE Mazibuko-Mbeje, SXH Mthembu… - International Journal of …, 2023 - mdpi.com
Brown adipose tissue (BAT) is increasingly recognized as the major therapeutic target to
promote energy expenditure and ameliorate diverse metabolic complications. There is a …

An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin

K Ziqubu, PV Dludla, SXH Mthembu… - Frontiers in …, 2023 - frontiersin.org
Brown adipose tissue (BAT), a thermoregulatory organ known to promote energy
expenditure, has been extensively studied as a potential avenue to combat obesity …

Origin and development of the adipose tissue, a key organ in physiology and disease

E Parra-Peralbo, A Talamillo, R Barrio - Frontiers in Cell and …, 2021 - frontiersin.org
Adipose tissue is a dynamic organ, well known for its function in energy storage and
mobilization according to nutrient availability and body needs, in charge of keeping the …

Batokines: mediators of inter-tissue communication (a mini-review)

FT Yang, KI Stanford - Current obesity reports, 2022 - Springer
Abstract Purpose of Review This review highlights aspects of brown adipose tissue (BAT)
communication with other organ systems and how BAT-to-tissue cross-talk could help …