Macrophage polarization and its role in liver disease
C Wang, C Ma, L Gong, Y Guo, K Fu, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
Macrophages are important immune cells in innate immunity, and have remarkable
heterogeneity and polarization. Under pathological conditions, in addition to the resident …
heterogeneity and polarization. Under pathological conditions, in addition to the resident …
Macrophages: versatile players in renal inflammation and fibrosis
Macrophages have important roles in immune surveillance and in the maintenance of
kidney homeostasis; their response to renal injury varies enormously depending on the …
kidney homeostasis; their response to renal injury varies enormously depending on the …
[HTML][HTML] The role of tumor-associated macrophages (TAMs) in tumor progression and relevant advance in targeted therapy
Q Yang, N Guo, Y Zhou, J Chen, Q Wei… - Acta Pharmaceutica Sinica …, 2020 - Elsevier
Macrophages have a leading position in the tumor microenvironment (TME) which paves the
way to carcinogenesis. Initially, monocytes and macrophages are recruited to the sites …
way to carcinogenesis. Initially, monocytes and macrophages are recruited to the sites …
Hypoxic glioma-derived exosomes deliver microRNA-1246 to induce M2 macrophage polarization by targeting TERF2IP via the STAT3 and NF-κB pathways
Exosomes are emerging as important elements that participate in intercellular
communication and tumor microenvironment modulation, but the exact mechanisms by …
communication and tumor microenvironment modulation, but the exact mechanisms by …
Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction
J Xu, J Zhang, Z Zhang, Z Gao, Y Qi, W Qiu, Z Pan… - Cell Death & …, 2021 - nature.com
Exosomes participate in intercellular communication and glioma microenvironment
modulation, but the exact mechanisms by which glioma-derived exosomes (GDEs) promote …
modulation, but the exact mechanisms by which glioma-derived exosomes (GDEs) promote …
Engineering cells for precision drug delivery: New advances, clinical translation, and emerging strategies
Cells have emerged as a promising new form of drug delivery carriers owing to their
distinguished advantages such as naturally bypassing immune recognition, intrinsic …
distinguished advantages such as naturally bypassing immune recognition, intrinsic …
[HTML][HTML] Glioma stem cells and their roles within the hypoxic tumor microenvironment
Tumor microenvironments are the result of cellular alterations in cancer that support
unrestricted growth and proliferation and result in further modifications in cell behavior …
unrestricted growth and proliferation and result in further modifications in cell behavior …
Mechanisms of macrophage plasticity in the tumor environment: manipulating activation state to improve outcomes
TD Ricketts, N Prieto-Dominguez, PS Gowda… - Frontiers in …, 2021 - frontiersin.org
Macrophages are a specialized class of innate immune cells with multifaceted roles in
modulation of the inflammatory response, homeostasis, and wound healing. While …
modulation of the inflammatory response, homeostasis, and wound healing. While …
Regulation of human macrophage M1–M2 polarization balance by hypoxia and the triggering receptor expressed on myeloid cells-1
Macrophages (Mf) are a heterogeneous population of tissue-resident professional
phagocytes and a major component of the leukocyte infiltrate at sites of inflammation …
phagocytes and a major component of the leukocyte infiltrate at sites of inflammation …
Immunosuppressive effects of hypoxia-induced glioma exosomes through myeloid-derived suppressor cells via the miR-10a/Rora and miR-21/Pten Pathways
X Guo, W Qiu, Q Liu, M Qian, S Wang, Z Zhang, X Gao… - Oncogene, 2018 - nature.com
While immunosuppressive environments mediated by myeloid-derived suppressor cells
(MDSCs) have been well documented in glioma patients, the mechanisms of MDSC …
(MDSCs) have been well documented in glioma patients, the mechanisms of MDSC …