The precise mapping and quantification of the numerous RNA modifications that are present
in tRNAs, rRNAs, ncRNAs/miRNAs, and mRNAs remain a major challenge and a top priority …

RNA modifications (epitranscriptome)–such as N6-methyladenosine (m6A), 5-
methylcytosine (m5C), and pseudouridine (Ψ)–modulate RNA processing, stability …

Trypanosomes are protozoan parasites that cycle between insect and mammalian hosts and
are the causative agent of sleeping sickness. Here, we describe the changes of …

Translational regulation impacts both pluripotency maintenance and cell differentiation. To
what degree the ribosome exerts control over this process remains unanswered …

Eukaryotic rRNAs and snRNAs are decorated with abundant 2′-O-methylated nucleotides
(Nm) that are predominantly synthesized by box C/D snoRNA-guided enzymes. In the model …

The parasite Trypanosoma brucei causes African sleeping sickness that is fatal to patients if
untreated. Parasite differentiation from a replicative slender form into a quiescent stumpy …

Leishmania is the causative agent of cutaneous and visceral diseases affecting millions of
individuals worldwide. Pseudouridine (Ψ), the most abundant modification on rRNA …

Epitranscriptomics heavily rely on chemical reagents for the detection, quantification, and
localization of modified nucleotides in transcriptomes. Recent years have seen a surge in …

As cardiovascular diseases continue to be the leading cause of death worldwide,
groundbreaking research is currently being conducted to mitigate their effects. This review …

There is growing evidence that post‐transcriptional RNA modifications are highly dynamic
and can be used to improve crop production. Although more than 172 unique types of RNA …