MicroRNA: function, detection, and bioanalysis

H Dong, J Lei, L Ding, Y Wen, H Ju, X Zhang - Chemical reviews, 2013 - ACS Publications
Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …

Imaging intracellular RNA distribution and dynamics in living cells

S Tyagi - natuRe methods, 2009 - nature.com
Powerful methods now allow the imaging of specific mRNAs in living cells. These methods
enlist fluorescent proteins to illuminate mRNAs, use labeled oligonucleotide probes and …

The RNA polymerase of influenza a virus: mechanisms of viral transcription and replication.

E Fodor - Acta virologica, 2013 - europepmc.org
The influenza A virus RNA genome segments are packaged in ribonucleoprotein complexes
containing RNA polymerase and nucleoprotein. The ribonucleoprotein is involved in the …

Influenza A virus polymerase: structural insights into replication and host adaptation mechanisms

S Boivin, S Cusack, RWH Ruigrok, DJ Hart - Journal of Biological Chemistry, 2010 - ASBMB
The heterotrimeric RNA-dependent RNA polymerase of influenza viruses catalyzes RNA
replication and transcription activities in infected cell nuclei. The nucleotide polymerization …

Single-molecule approaches to stochastic gene expression

A Raj, A van Oudenaarden - Annual review of biophysics, 2009 - annualreviews.org
Both the transcription of mRNAs from genes and their subsequent translation into proteins
are inherently stochastic biochemical events, and this randomness can lead to substantial …

Influenza virus non-structural protein NS1: interferon antagonism and beyond

D Marc - Journal of General Virology, 2014 - microbiologyresearch.org
Most viruses express one or several proteins that counter the antiviral defences of the host
cell. This is the task of non-structural protein NS1 in influenza viruses. Absent in the viral …

Role of the viral polymerase during adaptation of influenza A viruses to new hosts

B Gilbertson, M Duncan, K Subbarao - Current opinion in virology, 2023 - Elsevier
As a group, influenza-A viruses (IAV) infect a wide range of animal hosts, however, they are
constrained to infecting selected host species by species-specific interactions between the …

Influenza viruses and mRNA splicing: doing more with less

J Dubois, O Terrier, M Rosa-Calatrava - MBio, 2014 - Am Soc Microbiol
During their nuclear replication stage, influenza viruses hijack the host splicing machinery to
process some of their RNA segments, the M and NS segments. In this review, we provide an …

Influenza virus mRNA trafficking through host nuclear speckles

A Mor, A White, K Zhang, M Thompson, M Esparza… - Nature …, 2016 - nature.com
Influenza A virus is a human pathogen with a genome composed of eight viral RNA
segments that replicate in the nucleus. Two viral mRNAs are alternatively spliced. The …

Preparation and anti-influenza A virus activity of κ-carrageenan oligosaccharide and its sulphated derivatives

W Wang, P Zhang, GL Yu, CX Li, C Hao, X Qi… - Food chemistry, 2012 - Elsevier
Carrageenans, the sulphated galactans derived from red algae, are attracting increasing
interest in developing potential anti-viral drugs. In this study, low molecular weight κ …