Pathogenesis and virulence of herpes simplex virus
S Zhu, A Viejo-Borbolla - Virulence, 2021 - Taylor & Francis
Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2
(HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital …
(HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital …
The CD83 molecule–an important immune checkpoint
L Grosche, I Knippertz, C König, D Royzman… - Frontiers in …, 2020 - frontiersin.org
The CD83 molecule has been identified to be expressed on numerous activated immune
cells, including B and T lymphocytes, monocytes, dendritic cells, microglia, and neutrophils …
cells, including B and T lymphocytes, monocytes, dendritic cells, microglia, and neutrophils …
[HTML][HTML] Herpes simplex virus evasion of early host antiviral responses
EI Tognarelli, TF Palomino, N Corrales… - Frontiers in cellular …, 2019 - frontiersin.org
Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) have co-evolved with humans for
thousands of years and are present at a high prevalence in the population worldwide. HSV …
thousands of years and are present at a high prevalence in the population worldwide. HSV …
Mechanisms of sexually transmitted infection‐induced inflammation in women: implications for HIV risk
R Mwatelah, LR McKinnon, C Baxter… - Journal of the …, 2019 - Wiley Online Library
Introduction Globally, sexually transmitted infections (STI) affect> 300 million people
annually, and are a major cause of sexual and reproductive health complications in women …
annually, and are a major cause of sexual and reproductive health complications in women …
Griffithsin protects mice from genital herpes by preventing cell-to-cell spread
B Nixon, M Stefanidou, PMM Mesquita… - Journal of …, 2013 - Am Soc Microbiol
Griffithsin, which binds N-linked glycans on gp120 to prevent HIV entry, has the most potent
HIV-1 inhibitory activity described for any antiviral lectin and is being developed for topical …
HIV-1 inhibitory activity described for any antiviral lectin and is being developed for topical …
[HTML][HTML] IgG in cervicovaginal mucus traps HSV and prevents vaginal herpes infections
YY Wang, A Kannan, KL Nunn, MA Murphy… - Mucosal …, 2014 - Elsevier
IgG is the predominant immunoglobulin in cervicovaginal mucus (CVM), yet how
immunoglobulin G (IgG) in mucus can protect against infections is not fully understood. IgG …
immunoglobulin G (IgG) in mucus can protect against infections is not fully understood. IgG …
[HTML][HTML] Cytokines and chemokines: The vital role they play in herpes simplex virus mucosal immunology
JB Smith, JJ Herbert, NR Truong… - Frontiers in …, 2022 - frontiersin.org
Herpes simplex viruses (HSV) types 1 and 2 are ubiquitous infections in humans. They
cause orofacial and genital herpes with occasional severe complications. HSV2 also …
cause orofacial and genital herpes with occasional severe complications. HSV2 also …
Curcumin can decrease tissue inflammation and the severity of HSV-2 infection in the female reproductive mucosa
D Vitali, P Bagri, JM Wessels, M Arora… - International Journal of …, 2020 - mdpi.com
Herpes Simplex Virus Type 2 (HSV-2) is one of the most prevalent sexually transmitted
viruses and is a known risk factor for HIV acquisition in the Female Genital Tract (FGT) …
viruses and is a known risk factor for HIV acquisition in the Female Genital Tract (FGT) …
Evasion of early antiviral responses by herpes simplex viruses
PA Suazo, FJ Ibañez, AR Retamal-Díaz… - Mediators of …, 2015 - Wiley Online Library
Besides overcoming physical constraints, such as extreme temperatures, reduced humidity,
elevated pressure, and natural predators, human pathogens further need to overcome an …
elevated pressure, and natural predators, human pathogens further need to overcome an …
The low-cost compound lignosulfonic acid (LA) exhibits broad-spectrum anti-HIV and anti-HSV activity and has potential for microbicidal applications
SC Gordts, G Férir, T D'huys, MI Petrova, S Lebeer… - PLoS …, 2015 - journals.plos.org
Objectives Lignosulfonic acid (LA), a low-cost lignin-derived polyanionic macromolecule,
was extensively studied for its anti-HIV and anti-HSV activity in various cellular assays, its …
was extensively studied for its anti-HIV and anti-HSV activity in various cellular assays, its …