Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

The AMP-activated protein kinase (AMPK) is a central regulator of multiple metabolic
pathways and may have therapeutic importance for treating obesity, insulin resistance, type …

White fat stores excess energy, whereas brown and beige fat are thermogenic and dissipate
energy as heat. Thermogenic adipose tissues markedly improve glucose and lipid …

Stimulation of brown adipose tissue (BAT) thermogenesis in humans has emerged as an
attractive target to improve metabolic health. Pharmacological stimulations targeting the β 3 …

The demonstration of metabolically active brown adipose tissue (BAT) in humans primarily
using positron emission tomography coupled to computed tomography (PET/CT) with the …

Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

Brown (BAT) and white (WAT) adipose tissues play distinct roles in maintaining whole-body
energy homeostasis, and their dysfunction can contribute to non-alcoholic fatty liver disease …

Recruitment of brown adipose tissue (BAT) has emerged as a potential tool to combat
obesity and associated metabolic complications. Short-term cold acclimation has been …

Human brown adipose tissue (BAT) presence, metabolic activity, and estimated mass are
typically measured by imaging [18F] fluorodeoxyglucose (FDG) uptake in response to cold …

FGF21 decreases plasma triglycerides (TGs) in rodents and humans; however, the
underlying mechanism or mechanisms are unclear. In the present study, we examined the …