Neuromodulation in epilepsy: state-of-the-art approved therapies

P Ryvlin, S Rheims, LJ Hirsch, A Sokolov… - The Lancet …, 2021 - thelancet.com
Three neuromodulation therapies have been appropriately tested and approved in refractory
focal epilepsies: vagus nerve stimulation (VNS), deep brain stimulation of the anterior …

Advances in bioresorbable materials and electronics

Y Zhang, G Lee, S Li, Z Hu, K Zhao… - Chemical …, 2023 - ACS Publications
Transient electronic systems represent an emerging class of technology that is defined by an
ability to fully or partially dissolve, disintegrate, or otherwise disappear at controlled rates or …

Bioresorbable silicon electronics for transient spatiotemporal mapping of electrical activity from the cerebral cortex

KJ Yu, D Kuzum, SW Hwang, BH Kim, H Juul… - Nature materials, 2016 - nature.com
Bioresorbable silicon electronics technology offers unprecedented opportunities to deploy
advanced implantable monitoring systems that eliminate risks, cost and discomfort …

A new era in electroencephalographic monitoring? Subscalp devices for ultra–long‐term recordings

J Duun‐Henriksen, M Baud, MP Richardson… - …, 2020 - Wiley Online Library
Inaccurate subjective seizure counting poses treatment and diagnostic challenges and thus
suboptimal quality in epilepsy management. The limitations of existing hospital‐and home …

Brain‐responsive neurostimulation in patients with medically intractable mesial temporal lobe epilepsy

EB Geller, TL Skarpaas, RE Gross, RR Goodman… - …, 2017 - Wiley Online Library
Objective Evaluate the seizure‐reduction response and safety of mesial temporal lobe (MTL)
brain‐responsive stimulation in adults with medically intractable partial‐onset seizures of …

Managing drug-resistant epilepsy: challenges and solutions

L Dalic, MJ Cook - Neuropsychiatric disease and treatment, 2016 - Taylor & Francis
Despite the development of new antiepileptic drugs (AEDs),~ 20%–30% of people with
epilepsy remain refractory to treatment and are said to have drug-resistant epilepsy (DRE) …

Clinical utility of EEG in diagnosing and monitoring epilepsy in adults

WO Tatum, G Rubboli, PW Kaplan, SM Mirsatari… - Clinical …, 2018 - Elsevier
Electroencephalography (EEG) remains an essential diagnostic tool for people with epilepsy
(PWE). The International Federation of Clinical Neurophysiology produces new guidelines …

[HTML][HTML] Brain-responsive neurostimulation for epilepsy (RNS® System)

TL Skarpaas, B Jarosiewicz, MJ Morrell - Epilepsy research, 2019 - Elsevier
Controlled clinical trials in adults with medically intractable focal seizures treated with the
RNS® System demonstrate that closed-loop responsive neurostimulation to the seizure …

Practical considerations in epilepsy neurostimulation

HD Simpson, A Schulze‐Bonhage, GD Cascino… - …, 2022 - Wiley Online Library
Neuromodulation is a key therapeutic tool for clinicians managing patients with drug‐
resistant epilepsy. Multiple devices are available with long‐term follow‐up and real‐world …

Normative intracranial EEG maps epileptogenic tissues in focal epilepsy

JM Bernabei, N Sinha, TC Arnold, E Conrad, I Ong… - Brain, 2022 - academic.oup.com
Planning surgery for patients with medically refractory epilepsy often requires recording
seizures using intracranial EEG. Quantitative measures derived from interictal intracranial …