Implementation of microchip electrophoresis instrumentation for future spaceflight missions

PA Willis, JS Creamer, MF Mora - Analytical and bioanalytical chemistry, 2015 - Springer
We present a comprehensive discussion of the role that microchip electrophoresis (ME)
instrumentation could play in future NASA missions of exploration, as well as the current …

[HTML][HTML] In situ organic biosignature detection techniques for space applications

V Abrahamsson, I Kanik - Frontiers in Astronomy and Space Sciences, 2022 - frontiersin.org
The search for life in Solar System bodies such as Mars and Ocean Worlds (eg, Europa and
Enceladus) is an ongoing and high-priority endeavor in space science, even∼ five decades …

Detection of biosignatures by capillary electrophoresis mass spectrometry in the presence of salts relevant to ocean worlds missions

MF Mora, MGM Kok, A Noell, PA Willis - Astrobiology, 2022 - liebertpub.com
Capillary electrophoresis (CE) is a promising liquid-based technique for in situ chemical
analysis on ocean worlds that allows the detection of a wide range of organic molecules …

Recent trends in capillary and micro-chip electrophoretic instrumentation for field-analysis

M Zhang, SC Phung, P Smejkal, RM Guijt… - Trends in Environmental …, 2018 - Elsevier
Technical advances in the development of field-deployable capillary and microchip
electrophoretic instruments and reports of their deployment between 2013 and 2017 were …

Integrated chemiluminescence-based lab-on-chip for detection of life markers in extraterrestrial environments

A Nascetti, M Mirasoli, E Marchegiani… - Biosensors and …, 2019 - Elsevier
The detection of life markers is a high priority task in the exploration of the Solar System.
Biochips performing in-situ multiplex immunoassays are a very promising approach …

[HTML][HTML] Biological homochirality on the earth, or in the universe? A selective review

VA Davankov - Symmetry, 2018 - mdpi.com
The discovery of meteoritic alpha-amino acids with significant enantiomeric excesses of the
L-form has suggested that some cosmic factors could serve as the initial source for chiral …

Gas chromatographic separation of stereoisomers of non-protein amino acids on modified γ-cyclodextrin stationary phase

S Fox, H Strasdeit, S Haasmann, H Brückner - Journal of Chromatography A, 2015 - Elsevier
Stereoisomers (enantiomers and diastereoisomers) of synthetic, non-protein amino acids
comprising α-, β-, and γ-amino acids, including α, α-dialkyl amino acids, were converted into …

Supercritical CO2 and Subcritical H2O Analysis Instrument: Automated Lipid Analysis for In Situ Planetary Life Detection

V Abrahamsson, BL Henderson, A Friedman… - Analytical …, 2024 - ACS Publications
The search for extraterrestrial extant or extinct life in our Solar System will require highly
capable instrumentation and methods for detecting low concentrations of biosignatures. This …

[HTML][HTML] Inhabited or uninhabited? Pitfalls in the interpretation of possible chemical signatures of extraterrestrial life

S Fox, H Strasdeit - Frontiers in Microbiology, 2017 - frontiersin.org
The “Rare Earth” hypothesis—put forward by Ward and Brownlee in their 2000 book of the
same title—states that prokaryote-type organisms may be common in the universe but …

Gas chromatography coupled-to Fourier transform orbitrap mass spectrometer for enantioselective amino acid analyses: Application to pre-cometary organic analog

A Garcia, C Serra, QB Remaury, AD Garcia… - … of Chromatography A, 2023 - Elsevier
Gas chromatography (GC) is a separation technique commonly developed for targeted in
situ analyses in planetary space missions. It is coupled with low-resolution mass …