TGF-β/SMAD signaling regulation of mesenchymal stem cells in adipocyte commitment

SN Li, JF Wu - Stem cell research & therapy, 2020 - Springer
Adipocytes arising from mesenchymal stem cells (MSCs) requires MSC adipocyte
commitment and differentiation of preadipocytes to mature adipocytes. Several signaling …

[HTML][HTML] Transforming growth factor beta superfamily regulation of adipose tissue biology in obesity

MJ Lee - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2018 - Elsevier
Accumulation of dysfunctional white adipose tissues increases risks for cardiometabolic
diseases in obesity. In addition to white, brown or brite adipose tissues are also present in …

Beyond the bone: Bone morphogenetic protein signaling in adipose tissue

AM Blázquez‐Medela, M Jumabay… - Obesity …, 2019 - Wiley Online Library
The bone morphogenetic proteins (BMPs) belong to the same superfamily as related to
transforming growth factor β (TGFβ), growth and differentiation factors (GDFs), and activins …

Biological characteristics and osteogenic differentiation of ovine bone marrow derived mesenchymal stem cells stimulated with FGF-2 and BMP-2

S Gromolak, A Krawczenko, A Antończyk… - International Journal of …, 2020 - mdpi.com
Cell-based therapies using mesenchymal stem cells (MSCs) are a promising tool in bone
tissue engineering. Bone regeneration with MSCs involves a series of molecular processes …

Downregulation of DNA methyltransferase-3a ameliorates the osteogenic differentiation ability of adipose-derived stem cells in diabetic osteoporosis via Wnt/β-catenin …

M Zhang, Y Gao, Q Li, H Cao, J Yang, X Cai… - Stem cell research & …, 2022 - Springer
Background Diabetes-related osteoporosis (DOP) is a chronic disease caused by the high
glucose environment that induces a metabolic disorder of osteocytes and osteoblast …

IL-6 potentiates BMP-2-induced osteogenesis and adipogenesis via two different BMPR1A-mediated pathways

RL Huang, Y Sun, CK Ho, K Liu, QQ Tang, Y Xie… - Cell death & …, 2018 - nature.com
Recombinant human bone morphogenetic protein-2 (rhBMP-2) is widely used in the clinic
for bone defect reconstruction because of its powerful osteoinductive capacity. However …

Evaluation of the effect of donor weight on adipose stromal/stem cell characteristics by using weight-discordant monozygotic twin pairs

M Juntunen, S Heinonen, H Huhtala… - Stem Cell Research & …, 2021 - Springer
Background Adipose stromal/stem cells (ASCs) are promising candidates for future clinical
applications. ASCs have regenerative capacity, low immunogenicity, and …

Preparation and characterization of 3D hydroxyapatite/collagen scaffolds and its application in bone regeneration with bone morphogenetic protein-2

H Xie, S Ruan, M Zhao, J Long, X Ma, J Guo, X Lin - RSC advances, 2023 - pubs.rsc.org
Desirable bone engineering materials should have a conducive three-dimensional (3D)
structure and bioactive mediators for guided bone regeneration. In the present study …

[HTML][HTML] Concentrated growth factor promotes dental pulp cells proliferation and mineralization and facilitates recovery of dental pulp tissue

S Tian, J Wang, F Dong, N Du, W Li… - … medical journal of …, 2019 - ncbi.nlm.nih.gov
Background Dental pulp cells (DPCs) play vital roles in the recovery of dental pulp tissue.
Concentrated growth factor (CGF) can promote proliferation and mineralization of various …

The effects of maternal fish oil supplementation rich in n-3 PUFA on offspring-broiler growth performance, body composition and bone microstructure

YH Tompkins, C Chen, KM Sweeney, M Kim, BH Voy… - Plos one, 2022 - journals.plos.org
This study evaluated the effects of maternal fish oil supplementation rich in n-3 PUFA on the
performance and bone health of offspring broilers at embryonic development stage and at …