Tandem-catalysis-enabled highly chemoselective deoxygenative alkynylation and alkylation of tertiary amides: a versatile entry to functionalized α-substituted amines

XG Wang, W Ou, MH Liu, ZJ Liu… - Organic Chemistry …, 2022 - pubs.rsc.org
We report here the highly chemoselective catalytic reductive alkynylation and reductive
alkylation of tertiary amides to give propargylamines and α-branched amines, respectively …

Enantioselective total syntheses of marine natural products (+)-cylindricines C, D, E and their diastereomers

YH Huang, ZJ Liu, PQ Huang - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
A seven-step total synthesis of (+)-cylindricine D and epi-cylindricine D is described. The
efficiency relies on the highly diastereoselective reductive bis-functionalization of N, O …

A flexible enantioselective approach to 2, 5-disubstituted cis-decahydroquinolines

QW Lang, XY Qian, XL He, H Geng, JF Zheng… - Tetrahedron, 2022 - Elsevier
A flexible asymmetric approach to 2, 5-disubstituted cis-decahydroquinolines (DHQs) ring
system from glutaraldehyde and methyl (E)-5-nitropent-4-enoate is reported. The …

Tf2O-Mediated Cyclization of 7-Enamides: Bioinspired Construction of Fused Eight-Membered Carbocyclic Enimines and Enones

SJ Yu, JL Ye, YC Hong, PQ Huang - The Journal of Organic …, 2021 - ACS Publications
In this paper, we document the construction of functionalized and fused eight-membered
carbocycles by the triflic anhydride-mediated cyclization of 7-enamides. Taking advantage of …

Tf2O-Promoted Morgan–Walls Reaction: From a Flexible Approach to Functionalized Phenanthridines and Quinazolines to the Short and Divergent Total Syntheses of …

XY Su, PQ Huang - Synthesis, 2023 - thieme-connect.com
A new protocol for the direct transformation of secondary amides (N-acyl-o-xenylamines) to
phenanthridines under mild conditions is reported. The method features …