The Na V 1.4 sodium channel is highly expressed in skeletal muscle, where it carries almost
all of the inward Na+ current that generates the action potential, but is not present at …

Voltage-gated sodium (Nav) channels are essential for the rapid upstroke of action
potentials and the propagation of electrical signals in nerves and muscles. Defects of Nav …

Background Sudden infant death syndrome (SIDS) is the leading cause of post-neonatal
infant death in high-income countries. Central respiratory system dysfunction seems to …

Abstract See Cannon (doi: 10.1093/brain/awv400) for a scientific commentary on this article.
Congenital myopathies are a clinically and genetically heterogeneous group of muscle …

The periodic paralyses are a group of skeletal muscle channelopathies characterizeed by
intermittent attacks of muscle weakness often associated with altered serum potassium …

Background: Skeletal muscle ion channelopathies include non-dystrophic myotonias (NDM),
periodic paralyses (PP), congenital myasthenic syndrome, and recently identified congenital …

Skeletal muscle sodium channelopathies : Current Opinion in Neurology Skeletal muscle
sodium channelopathies : Current Opinion in Neurology Log in or Register Subscribe to …

Accurate approaches for quantifying muscle fibers are essential in biomedical research and
meat production. In this study, we address the limitations of existing approaches for …

Dominantly inherited channelopathies of the skeletal muscle voltage-gated sodium channel
NaV1. 4 include hypokalaemic and hyperkalaemic periodic paralysis (hypoPP and hyperPP) …

Polyglutamine expansions in the huntingtin gene cause Huntington's disease (HD).
Huntingtin is ubiquitously expressed, leading to pathological alterations also in peripheral …