Central nervous system (CNS) disorders are a therapeutic area in drug discovery where
demand for new treatments greatly exceeds approved treatment options. This is complicated …

Introduction: Docking and structure-based virtual screening (VS) have been standard
approaches in structure-based design for over two decades. However, our understanding of …

Most studies related to hemp are focused on Cannabidiol (CBD) and Tetrahydrocannabinol
(THC); however, up to 120 types of phytocannabinoids are present in hemp. Hemp leaves …

Cannabinoid receptor ligands are renowned as being therapeutically crucial for treating
diverse health disorders. Phenylspirodrimanes are meroterpenoids with unique and varied …

Magnolia grandiflora L.(Magnoliaceae) is a plant of considerable medicinal significance; its
flowers and seeds have been used in various traditional remedies. Radioligand binding …

Background and Purpose Δ9‐Tetrahydrocannabinolic acid (Δ9‐THCA‐A), the precursor of
Δ9‐THC, is a non‐psychotropic phytocannabinoid that shows PPARγ agonist activity. Here …

Abstract 'Diabesity'refers to a rising epidemic indicated by the intricate relationship between
obesity and diabetes. The global prevalence of these coexisting, insidious diseases …

Idiopathic membranous nephropathy (IMN) is one of the main types of chronic kidney
disease in adults and one of the most common causes of end-stage renal disease. In recent …

To provide a comprehensive framework of the current information on the potency and
efficacy of interaction between phyto-and synthetic cannabinoids and their respective …

Machaeriols and machaeridiols are unique hexahydrodibenzopyran-type aralkyl
phytocannabinoids isolated from Machaerium Pers. Earlier studies of machaeriol A (1) and …