Dopamine neuron systems in the brain: an update

A Björklund, SB Dunnett - Trends in neurosciences, 2007 - cell.com
The basic organization of the catecholamine-containing neuronal systems and their axonal
projections in the brain was initially worked out using classical histofluorescence techniques …

Compensatory mechanisms in Parkinson's disease: circuits adaptations and role in disease modification

J Blesa, I Trigo-Damas, M Dileone, NLG Del Rey… - Experimental …, 2017 - Elsevier
The motor features of Parkinson's disease (PD) are well known to manifest only when striatal
dopaminergic deficit reaches 60–70%. Thus, PD has a long pre-symptomatic and pre-motor …

Functional anatomy of the basal ganglia. II. The place of subthalamic nucleus and external pallidium in basal ganglia circuitry

A Parent, LN Hazrati - Brain research reviews, 1995 - Elsevier
The subthalamic nucleus and the external pallidum (GPe) are classically viewed as part of
the so-called indirect pathway, which acts in concert with the direct pathway. The direct and …

The subthalamic nucleus in the context of movement disorders

C Hamani, JA Saint‐Cyr, J Fraser, M Kaplitt… - Brain, 2004 - academic.oup.com
The subthalamic nucleus (STN) has been regarded as an important modulator of basal
ganglia output. It receives its major afferents from the cerebral cortex, thalamus, globus …

Diffusion tensor fiber tracking shows distinct corticostriatal circuits in humans

S Lehéricy, M Ducros, PF Van De Moortele… - Annals of …, 2004 - Wiley Online Library
A landmark of corticostriatal connectivity in nonhuman primates is that cortical connections
are organized into a set of discrete circuits. Each circuit is assumed to perform distinct …

The connections of the dopaminergic system with the striatum in rats and primates: an analysis with respect to the functional and compartmental organization of the …

D Joel, I Weiner - Neuroscience, 2000 - Elsevier
This Commentary compares the connections of the dopaminergic system with the striatum in
rats and primates with respect to two levels of striatal organization: a tripartite functional …

Functional and pathophysiological models of the basal ganglia

T Wichmann, MR DeLong - Current opinion in neurobiology, 1996 - Elsevier
Because of new data, anatomical and functional models of the basal ganglia in normal and
pathological conditions (eg Parkinson's and Huntington's diseases) have recently come …

[HTML][HTML] Coincident but distinct messages of midbrain dopamine and striatal tonically active neurons

G Morris, D Arkadir, A Nevet, E Vaadia, H Bergman - Neuron, 2004 - cell.com
Midbrain dopamine and striatal tonically active neurons (TANs, presumed acetylcholine
interneurons) signal behavioral significance of environmental events. Since striatal …

Abnormal spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism

M Filion - Brain research, 1991 - Elsevier
The goal of the study was to determine abnormalities in the spontaneous activity of globus
pallidus at the output of the basal ganglia, in cynomolgus monkeys rendered parkinsonian …

Extrinsic connections of the basal ganglia

A Parent - Trends in neurosciences, 1990 - cell.com
Recent neuroanatomical studies undertaken with various powerful neural tracing methods
have radically changed our concept of the organization of the basal ganglia. This paper …