Background The risks of local recurrence and treatment-related morbidity need to be
balanced after local excision of early rectal cancer. The aim of this meta-analysis was to …

Background A uniform definition of a clinical near-complete response (near-CR) after
neoadjuvant (chemo) radiotherapy for rectal cancer is lacking. A clear definition is necessary …

Background Adequate MRI-based staging of early rectal cancers is essential for decision-
making in an era of organ-conserving treatment approaches. The aim of this population …

Surgery remains the cardinal treatment in colorectal cancers but changes in bowel habits
after rectal cancer surgery are common and disabling conditions that affect patients' quality …

The current standard of care for the treatment of locally advanced rectal cancer includes
neoadjuvant chemoradiation (nCRT) followed by total mesorrectal excision (TME). The …

Aim The aim of this study was to evaluate interobserver variability between individual
pathologists and a panel of pathologists in the histopathological assessment of advanced …

Background By improved surgical technique such as total mesorectal excision (TME),
multimodal treatment and advances in imaging survival and an increased rate of sphincter …

Rectal resection is a common practice for colorectal surgeons. The causes of this procedure
are varied. The most frequent is cancer, but also inflammatory bowel disease …

Background With the well established shift to neoadjuvant treatment for locally advanced
rectal cancer, there is increasing focus on the use of radiosensitizers to improve the efficacy …

Local excision following chemoradiotherapy in rectal cancer is an organ-preserving
procedure which aims at reducing morbidity and functional disorders associated with total …