Cerebellum lecture: the cerebellar nuclei—core of the cerebellum

JM Kebschull, F Casoni, GG Consalez, D Goldowitz… - The Cerebellum, 2024 - Springer
The cerebellum is a key player in many brain functions and a major topic of neuroscience
research. However, the cerebellar nuclei (CN), the main output structures of the cerebellum …

Recent advances in the understanding of specific efferent pathways emerging from the cerebellum

S Kang, S Jun, SJ Baek, H Park, Y Yamamoto… - Frontiers in …, 2021 - frontiersin.org
The cerebellum has a long history in terms of research on its network structures and motor
functions, yet our understanding of them has further advanced in recent years owing to …

Cerebellar coordination of neuronal communication in cerebral cortex

SS McAfee, Y Liu, RV Sillitoe, DH Heck - Frontiers in systems …, 2022 - frontiersin.org
Cognitive processes involve precisely coordinated neuronal communications between
multiple cerebral cortical structures in a task specific manner. Rich new evidence now …

Diverse inhibitory projections from the cerebellar interposed nucleus

EN Judd, SM Lewis, AL Person - Elife, 2021 - elifesciences.org
The cerebellum consists of parallel circuit modules that contribute to diverse behaviors,
spanning motor to cognitive. Recent work employing cell-type-specific tracing has identified …

Climbing fibers provide essential instructive signals for associative learning

NT Silva, J Ramírez-Buriticá, DL Pritchett… - Nature …, 2024 - nature.com
Supervised learning depends on instructive signals that shape the output of neural circuits to
support learned changes in behavior. Climbing fiber (CF) inputs to the cerebellar cortex …

Dynamic modulation of activity in cerebellar nuclei neurons during pavlovian eyeblink conditioning in mice

MM Ten Brinke, SA Heiney, X Wang, M Proietti-Onori… - Elife, 2017 - elifesciences.org
While research on the cerebellar cortex is crystallizing our understanding of its function in
learning behavior, many questions surrounding its downstream targets remain. Here, we …

Cerebellar plasticity and associative memories are controlled by perineuronal nets

D Carulli, R Broersen, F de Winter… - Proceedings of the …, 2020 - National Acad Sciences
Perineuronal nets (PNNs) are assemblies of extracellular matrix molecules, which surround
the cell body and dendrites of many types of neuron and regulate neural plasticity. PNNs are …

Molecular layer interneurons shape the spike activity of cerebellar Purkinje cells

AM Brown, M Arancillo, T Lin, DR Catt, J Zhou… - Scientific reports, 2019 - nature.com
Purkinje cells receive synaptic input from several classes of interneurons. Here, we address
the roles of inhibitory molecular layer interneurons in establishing Purkinje cell function in …

Cerebellospinal neurons regulate motor performance and motor learning

A Sathyamurthy, A Barik, CI Dobrott, KJE Matson… - Cell reports, 2020 - cell.com
To understand the neural basis of behavior, it is important to reveal how movements are
planned, executed, and refined by networks of neurons distributed throughout the nervous …

Synaptic mechanisms for associative learning in the cerebellar nuclei

R Broersen, C Albergaria, D Carulli, MR Carey… - Nature …, 2023 - nature.com
Associative learning during delay eyeblink conditioning (EBC) depends on an intact
cerebellum. However, the relative contribution of changes in the cerebellar nuclei to learning …