[HTML][HTML] Contemporary techniques and potential transungual drug delivery nanosystems for the treatment of onychomycosis
WH Abd-Elsalam, SM Abouelatta - AAPS PharmSciTech, 2023 - Springer
The humanoid nail is considered an exceptional protective barrier that is formed mainly from
keratin. Onychomycosis is the cause of 50% of nail infections that is generally caused by …
keratin. Onychomycosis is the cause of 50% of nail infections that is generally caused by …
[HTML][HTML] Itraconazole and difluorinated-curcumin containing chitosan nanoparticle loaded hydrogel for amelioration of onychomycosis
Onychomycosis is a nail infection caused by a fungus, Trichophyton mentagrophytes, that is
responsible for major nail infections. The best method suited for treating such infections …
responsible for major nail infections. The best method suited for treating such infections …
[HTML][HTML] Antifungal nail lacquer for enhanced transungual delivery of econazole nitrate
The fungal disease of the nail, onychomycosis, which is also the most prevalent nail
disturbance, demands effective topical treatment options considering the possible adverse …
disturbance, demands effective topical treatment options considering the possible adverse …
Design and evaluation of microemulsion-based efinaconazole formulations for targeted treatment of onychomycosis through transungual route: Ex vivo and nail …
The onychomycosis treatment remains a big challenge for onychologist due to the shorter
nail residence time of topical formulations and the lack of availability of novel formulations in …
nail residence time of topical formulations and the lack of availability of novel formulations in …
[HTML][HTML] Constant Voltage Iontophoresis Technique to Deliver Terbinafine via Transungual Delivery System: Formulation Optimization Using Box–Behnken Design …
Topical therapy of antifungals is primarily restricted due to the low innate transport of drugs
through the thick multi-layered keratinized nail plate. The objective of this investigation was …
through the thick multi-layered keratinized nail plate. The objective of this investigation was …
Design, characterization, and evaluation of efinaconazole loaded poly (D, L-lactide-co-glycolide) nanocapsules for targeted treatment of onychomycosis
Polymeric nanocapsules have recently gained increased interest as antifungal delivery
carriers owing to a microstructure composed of a liquid/solid core containing a drug that is …
carriers owing to a microstructure composed of a liquid/solid core containing a drug that is …
[HTML][HTML] Assessment of the nail penetration of antifungal agents, with different physico-chemical properties
H Davies-Strickleton, J Cook, S Hannam, R Bennett… - Plos one, 2020 - journals.plos.org
Onychomycosis, or fungal nail infection, is a common fungal infection largely caused by
dermatophyte fungi, such as Trichophyton rubrum or Trichophyton mentagrophytes, which …
dermatophyte fungi, such as Trichophyton rubrum or Trichophyton mentagrophytes, which …
[HTML][HTML] Preparation of topical itraconazole with enhanced skin/nail permeability and in vivo antifungal efficacy against superficial mycosis
In this study, a stable and highly skin-permeable topical delivery system for itraconazole
(ITZ) was designed to provide effective treatment against superficial mycosis. Herein, ITZ …
(ITZ) was designed to provide effective treatment against superficial mycosis. Herein, ITZ …
Gallic acid loaded self-nano emulsifying hydrogel-based drug delivery system against onychomycosis
Aim: To developed and investigate gallic acid (GA) loaded self-nanoemulsifying drug
delivery systems (SNEDDS) for treating onychomycosis via transungual route. Materials & …
delivery systems (SNEDDS) for treating onychomycosis via transungual route. Materials & …
In-vitro and In-vivo characterization of anti-onychomycotic transungual patches-A systematic review
L Thampi, EJ Gini - Research Journal of Pharmacy and …, 2023 - indianjournals.com
Transungual drug delivery systems distribute therapeutic agents through the human nail, a
unique way for delivering medications for nail disorders caused by fungal infections. The …
unique way for delivering medications for nail disorders caused by fungal infections. The …