Cancer mRNA vaccines: clinical advances and future opportunities
EJ Sayour, D Boczkowski, DA Mitchell… - Nature Reviews Clinical …, 2024 - nature.com
Abstract mRNA vaccines have been revolutionary in terms of their rapid development and
prevention of SARS-CoV-2 infections during the COVID-19 pandemic, and this technology …
prevention of SARS-CoV-2 infections during the COVID-19 pandemic, and this technology …
Recent Advances in Biomimetic Strategies for the Immunotherapy of Glioblastoma
H You, S Geng, S Li, M Imani, D Brambilla, T Sun… - Biomaterials, 2024 - Elsevier
Immunotherapy is regarded as one of the most promising approaches for treating tumors,
with a multitude of immunotherapeutic thoughts currently under consideration for the lethal …
with a multitude of immunotherapeutic thoughts currently under consideration for the lethal …
[HTML][HTML] Expanded specific T cells to hypomutated regions of the SARS-CoV-2 using mRNA electroporated antigen-presenting cells
The COVID-19 pandemic has caused about seven million deaths worldwide. Preventative
vaccines have been developed including Spike gp mRNA-based vaccines that provide …
vaccines have been developed including Spike gp mRNA-based vaccines that provide …
Pericytes Are Immunoregulatory Cells in Glioma Genesis and Progression
M Martinez-Morga, D Garrigos… - International Journal of …, 2024 - mdpi.com
Vascular co-option is a consequence of the direct interaction between perivascular cells,
known as pericytes (PCs), and glioblastoma multiforme (GBM) cells (GBMcs). This process …
known as pericytes (PCs), and glioblastoma multiforme (GBM) cells (GBMcs). This process …
Beyond the danger signal: RNA aggregates orchestrate immunotherapy
QTH Shubhra, T Feczkó, Q Cai - Trends in Molecular Medicine, 2024 - cell.com
Mendez-Gomez et al. recently demonstrated the transformative potential of RNA-lipid
particle aggregates (RNA-LPAs) in immunotherapy. By reprogramming the tumor …
particle aggregates (RNA-LPAs) in immunotherapy. By reprogramming the tumor …
mRNA challenge predicts brain cancer immunogenicity and response to checkpoint inhibitors
To prospectively determine whether brain tumors will respond to immune checkpoint
inhibitors (ICIs), we developed a novel mRNA vaccine as a viral mimic to elucidate cytokine …
inhibitors (ICIs), we developed a novel mRNA vaccine as a viral mimic to elucidate cytokine …