Intracellular bacterial pathogens cause a wide range of diseases and significantly contribute
to the morbidity and mortality associated with infectious diseases worldwide (1‐16)(Table 1) …

Francisella tularensis is a highly-infectious bacterium that causes the rapid, and often lethal
disease, tularemia. Many studies have been performed to identify and characterize the …

Acinetobacter baumannii (Ab) is a global emerging bacterium causing nosocomial infections
such as pneumonia, meningitis, bacteremia and soft tissue infections especially in intensive …

Inhalation of Francisella tularensis (Ft) causes acute and fatal pneumonia. The lung cytokine
milieu favors exponential Ft replication, but the mechanisms underlying acute pathogenesis …

Francisella tularensis infects several cell types including neutrophils, and aberrant
neutrophil accumulation contributes to tissue destruction during tularaemia. We …

Mice lacking expression of the homologous phosphatases Sts-1 and Sts-2 (Sts−/− mice) are
resistant to disseminated candidiasis caused by the fungal pathogen Candida albicans. To …

Francisella tularensis is a Gram-negative, facultative intracellular pathogen and the
causative agent of tularemia. Previous studies with the attenuated live vaccine strain (LVS) …

Francisella tularensis is a zoonotic pathogen and the causative agent of tularemia. F.
tularensis replicates to high levels within the cytosol of macrophages and other host cells …

Francisella tularensis, the causative agent of tularemia, lacks typical bacterial virulence
factors and toxins but still exhibits extreme virulence. The bacterial multidrug efflux systems …

Macrophage-pathogen interaction is a complex process and the outcome of this tag-of-war
for both sides is to live or die. Without attempting to be comprehensive, this review will …