Human iPSC banking: barriers and opportunities

CY Huang, CL Liu, CY Ting, YT Chiu… - Journal of biomedical …, 2019 - Springer
The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for
personalized cell therapies and ushered in new opportunities for regenerative medicine …

Y-box binding proteins in mRNP assembly, translation, and stability control

D Mordovkina, DN Lyabin, EA Smolin, EM Sogorina… - Biomolecules, 2020 - mdpi.com
Y-box binding proteins (YB proteins) are DNA/RNA-binding proteins belonging to a large
family of proteins with the cold shock domain. Functionally, these proteins are known to be …

Identification of long noncoding RNA H19 as a new biomarker and therapeutic target in right ventricular failure in pulmonary arterial hypertension

J Omura, K Habbout, T Shimauchi, WH Wu… - Circulation, 2020 - Am Heart Assoc
Background: Right ventricular (RV) function is the major determinant for both functional
capacity and survival in patients with pulmonary arterial hypertension (PAH). Despite the …

NPRC deletion attenuates cardiac fibrosis in diabetic mice by activating PKA/PKG and inhibiting TGF-β1/Smad pathways

L Meng, Y Lu, X Wang, C Cheng, F Xue, L Xie… - Science …, 2023 - science.org
Cardiac fibrosis plays a key role in the progression of diabetic cardiomyopathy (DCM).
Previous studies demonstrated the cardioprotective effects of natriuretic peptides. However …

The roles of lncRNA in myocardial infarction: molecular mechanisms, diagnosis biomarkers, and therapeutic perspectives

L Xie, Q Zhang, J Mao, J Zhang, L Li - Frontiers in cell and …, 2021 - frontiersin.org
In recent years, long non-coding RNAs (lncRNAs) have been demonstrated to be associated
with many physiological and pathological processes in cardiac. Recent studies have shown …

LncRNA CRNDE facilitates epigenetic suppression of CELF2 and LATS2 to promote proliferation, migration and chemoresistance in hepatocellular carcinoma

SC Xie, JQ Zhang, XL Jiang, YY Hua, SW Xie… - Cell death & …, 2020 - nature.com
Our study aimed to investigate the expression, functional significance, and related
mechanism of long noncoding RNA CRNDE (colorectal neoplasia differentially expressed) …

[HTML][HTML] The regulation of circRNA and lncRNAprotein binding in cardiovascular diseases: Emerging therapeutic targets

H Zhao, Z Tan, J Zhou, Y Wu, Q Hu, Q Ling… - Biomedicine & …, 2023 - Elsevier
Noncoding ribonucleic acids (ncRNAs) are a class of ribonucleic acids (RNAs) that carry
cellular information and perform essential functions. This class encompasses various RNAs …

Long non-coding RNAs in cardiovascular diseases: potential function as biomarkers and therapeutic targets of exercise training

CCM Correia, LF Rodrigues, BR de Avila Pelozin… - Non-coding RNA, 2021 - mdpi.com
Despite advances in treatments and therapies, cardiovascular diseases (CVDs) remain one
of the leading causes of death worldwide. The discovery that most of the human genome …

[HTML][HTML] Circulating exosomes in cardiovascular disease: Novel carriers of biological information

Q Liu, H Piao, Y Wang, D Zheng, W Wang - Biomedicine & …, 2021 - Elsevier
Exosomes are a group of nanosized extracellular vesicles that include various bioactive
nucleic acids, lipids, and proteins. They originate from membrane invagination and are …

Long Noncoding RNA H19: A Novel Therapeutic Target Emerging in Oncology Via Regulating Oncogenic Signaling Pathways

B Wu, Y Zhang, Y Yu, C Zhong, Q Lang… - Frontiers in Cell and …, 2021 - frontiersin.org
Long noncoding RNA H19 (H19) is an imprinting gene with only maternal expression that is
involved in regulating different processes in various types of cells. Previous studies have …