Hypoxia is a common feature of solid tumors, and develops because of the rapid growth of
the tumor that outstrips the oxygen supply, and impaired blood flow due to the formation of …

Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

The use of synthetic, natural, or biological agents to minimize the occurrence of cancer in
healthy individuals is defined as cancer chemoprevention. Chemopreventive agents inhibit …

Abstract Cucurbitacin B (CuB, C 32 H 46 O 8), the most abundant and active member of
cucurbitacins, which are highly oxidized tetracyclic triterpenoids. Cucurbitacins are widely …

Since ancient times, plants have been an extensive reservoir of bioactive compounds with
therapeutic interest for new drug development and clinical application. Cucurbitacins are a …

Since last two decades, the major cancer research has focused on understanding the
characteristic properties and mechanism of formation of Cancer stem cells (CSCs), due to …

Objective Recent discoveries verify that long non-coding RNAs (lncRNAs) are important
functional regulators involved in non-small cell lung cancer (NSCLC) progression. However …

Cancer is one of the most important healthcare matters, with the worst prognosis but the best
possibilities for scientific development. It is likely to increase in the future and cause global …

Epigenetic research has the potential to improve our understanding of the pathogenesis of
cancer, specifically non-small-cell lung cancer, and support our efforts to personalize the …

Since the initial discovery of the oncogenic activity of WNT ligands our understanding of the
complex roles for WNT signaling pathways in lung cancers has increased substantially. In …